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Research Scientist-Immune Cell Redirection and Strategy

Employer
Eli Lilly and Company
Location
New York, NY, United States
Start date
Oct 21, 2019

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Discipline
Marketing, Science/R&D, Biotechnology
Required Education
Associate Degree
Position Type
Full time
Hotbed
Best Places to Work

Job Details

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 39,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.

#WeAreLilly

Responsibilities

Lilly's Immuno-Oncology Research and Development Center of Excellence in New York City is seeking a highly motivated Scientist to contribute to the development of cancer therapeutics in the Cancer Immunobiology department. The ideal scientist is expected to have a broad knowledge of cancer immunology with prior academic and/or industry experience and publications in the field.

You will be responsible for leading a group of scientists to support drug discovery and development in the area of T cell redirection within the immune oncology discovery area at the Lilly NY laboratories. Some responsibilities will be in contributing to novel redirection strategies as well as the overall Immuno-Oncology portfolio. Both target identification and target validation work will be required, including independently designing and carrying out experiments, directly overseeing Research Associates in their day-to-day work, and utilizing the broader Lilly resources in a matrixed fashion to achieve goals. Ultimately it is expected that drug candidates will be carried into clinical development. This role involves both leading aspects of laboratory experiments as well as performing laboratory experiments which are designed to understand the mechanism of action of pipeline cancer therapeutics. Examples include but are not limited to
  • developing and performing in vitro and in vivo models and assays;
  • mammalian cell culture (primary immune cell isolation/culture), transfections, stable clone generation; flow cytometry and immunophenotyping;
  • cell based and immunological assays including proliferation, effector function, reporter assays, T cell activation, antigen specific T cell isolation and characterization, T cell tumor killing.

You may also function as scientific team lead including leading and participating in project team meetings and providing written and verbal communication of work, presentation of data and data summaries internally and externally as needed.

Do you have a broad understanding of basic immunology as well as cancer immunobiology? This includes expertise in aspects of T cell priming, expansion and suppression. Experience in the area of T cell redirection is critical. It is desired to also have expertise in mechanisms of tumor mediated immune suppression. Excellent communication skills and the ability to work well independently and in a team setting are required in this role. Collaboration and teamwork are cornerstones of our research requiring you to work both independently as part of a multi-disciplinary teams and across functional areas.
51636BR

Basic Qualifications
  • PhD in Biological Sciences (e.g. Immunology, Tumor Immunology, Cell Biology or closely related discipline).


Additional Skills/Preferences
  • Prior post-doctoral and/or industry research experience in the Immuno-Oncology setting highly preferred.


Additional Information
Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Company

Science has been our calling from the beginning. Colonel Eli Lilly founded the company in 1876 and charged employees to “take what you find here and make it better and better.” More than 147 years later, we remain committed to his vision through every aspect of our business and the people we serve, starting with discovering the best treatments for those who take our medicines and extending to health care professionals, employees and the communities in which we live. Moreover, you can also count on the team at Lilly to be incredibly civic-minded, supporting our communities through philanthropy, volunteerism, and a creative and innovative can-do spirit. 

Company info
Location
893 S Delaware St
Indianapolis
Indiana
46285
United States

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