Scientist, Bispecific Antibodies

Location
Tarrytown, NY
Posted
Oct 19, 2019
Ref
17620BR
Required Education
Doctorate/PHD/MD
Position Type
Full time
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases.

Summary:
We are seeking a highly talented and innovative Ph.D. scientist to join the Bispecific Antibodies Department at Regeneron. The successful candidate will lead the effort to develop novel bispecific molecules across multiple therapeutic areas such as oncology, immunology, infectious disease, muscle/metabolism and neurosciences in our state-of-the-art research facility. The candidate will have the opportunity to collaborate and work with topline scientists in a world-class scientific environment. The ideal candidate will also be responsible to develop novel tools and platforms to enable efficient screening and characterization of these novel molecules. The qualified candidate should have a strong background in antibody/protein engineering and expertise in at least one of following areas: oncology/metabolism/infectious disease.

Responsibilities:

• Design and construct novel bispecific antibodies and related molecules with the combination of molecular modeling tools and in-depth understanding of the target biology

• Design and construct rational and/or randomization library via mutagenesis and display systems

• Express and characterize molecules in vitro using biochemical and cell-based assays

• Perform high throughput antibody production and screening

• Troubleshoot experiments with minimal guidance. Independently analyze data and provide accurate summary to management

• Present data at group and inter-departmental meetings with scientific rigor

• Maintain complete, accurate, and timely record of experiments and data analysis

• Keep abreast of the latest technology and advancement in antibody engineering and therapeutic areas

• Develop in-depth scientific knowledge in area of research focus, propose new ideas and contribute to decisions on project direction intellectually

• Collaboration with diverse functional groups within the company
Requirements:

• A PhD in Biochemistry, Molecular Biology, Immunology or a related field with 3-5 years post-doctoral or industry experience

• Significant experience in antibody/protein engineering, structural biology and immuno-oncology with a proven track of record of innovative solutions

• Experiences in phage, yeast or mammalian display

• Excellent communication skills, ability to work productively in a fast-paced and collaborative team environment

• Attention to detail, critical thinking, and an aptitude for learning are also key elements of the position

• Broad knowledge in disease biology is preferred

• Past experience in automation or high throughput screening is preferred
This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business.

To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.