R&D Associate, Neuroscience

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases.

Summary:
We are seeking a passionate and results-oriented Research Associate to join our dynamic Neuroscience research team. Team members work both collaboratively and independently to study new therapeutic strategies for treating serious neurological disorders including neurodegenerative disorders and chronic pain. Job responsibilities include designing and using cell-based assays and preclinical behavioral assessments to support the development of novel therapeutics. In addition, successful candidate will work to support technology development for improving the delivery of therapeutics into the nervous system as we strive to innovate new approaches to treating neurological diseases.

Responsibilities:

• Construct cell-based assays for studying mechanisms of neurological disorders and for conducting initial evaluations of novel therapeutic strategies.

• Develop and evaluate new animal models of disease, as needed

• Design and perform behavioral assessments in animal models of pain and/or neurological diseases

• Characterize the efficacy of novel therapeutics using in vivo animal models or in vitro assays

• Compare various administration routes for novel therapeutics (intraperitoneal, subcutaneous, intracerebroventricular, and intrathecal)

• Support technology development, including the development of innovative delivery modalities for targeting therapeutics to specific cell types in the nervous system

• Engage in technical trouble shooting with minimal supervision

• Dissect tissues (DRGs, trigeminal ganglia, sympathetic ganglia, spinal cord, and different regions of the brain) and conduct downstream assays such as RNAseq, RNAscope, ELISA, immunohistochemistry, and/or western blotting to evaluate efficacy or distribution

• Compile data, perform advanced data analyses, prepare graphs/tables, and present results at internal meetings

• Keep up-to-date and well-organized records of experiments

Requirements:

Bachelor or MS degree in Neuroscience with 2-3 years experience

• Tissue dissection (DRG, trigeminal ganglion, sympathetic ganglion, spinal cord and different regions of the brain) for downstream assays such as RNAseq, RNAscope, Elisa, IHC or WB

• Intraperitoneal, intracerebroventricular and intrathecal injections experience required

• Experience with neurological and/or pain behavioral assessments required

• viral gene delivery experience a plus

• immunocytochemistry & immunohistochemistry a plus

• Experience with western blotting and Elisa required

• Basic molecular biology laboratory skills

• Ability to work independently

• Excellent communication skills

This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business.

To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.