Manufacturing Team Lead - GMP Downstream (2nd Shift)

Location
Austin, TX, USA
Posted
Oct 18, 2019
Ref
98615
Required Education
Bachelors Degree
Position Type
Full time
Company Description:

Molecular Templates is a clinical stage biopharmaceutical company focused on the discovery and development of differentiated, targeted, biologic therapeutics for cancer. We believe our proprietary biologic drug platform technology, referred to as engineered toxin bodies, or ETBs, provides a differentiated mechanism of action that may address some of the limitations associated with currently available cancer therapeutics. ETBs utilize a genetically engineered form of Shiga-like Toxin A subunit, or SLTA, a ribosome inactivating bacterial protein, that can be targeted to specifically destroy cancer cells. Additional information about Molecular Templates can be obtained at www.mtem.com.

Position Overview:

Molecular Templates is seeking an energetic and highly motivated professional to support downstream processing of therapeutic proteins. This position will perform functions related to production and GMP manufacturing operations, including scheduling and execution of protein purification steps. Equipment, facility, process and people readiness and understanding will be necessary to deliver quality ETBs, the next generation of immunotoxins, to patients in clinical trials. The Team Lead will provide on-the-floor execution and leadership support to bioprocessing unit operations requiring excellent technical, communication and teamwork skills. The Team Lead will be responsible for adhering to Standard Operating Procedure (SOP) guidelines, Good Manufacturing Practices and all safety requirements in a state-of-the-art biologics manufacturing facility.

Job Responsibilities will include:
  • Perform protein purification for downstream manufacturing activities
  • Document and verify production steps in accordance with manufacturing instructions
  • Develop and adhere to production schedules and timelines
  • Work cross-functionally to achieve team goals
  • Partner with Quality Assurance personnel to deliver quality product
  • Provide direction and coaching to team members during bioprocessing manufacturing
  • Communicate status, actions and drive improvement on key performance indicators
  • Ensure safety, compliance and Right-First-Time execution
  • Support room and equipment preparation for manufacturing operations
  • Maintain readiness of materials, rooms and equipment for operations
  • Identify solutions and problem solve technical and operational challenges
  • Work with internal and external subject matter experts to implement new technology, equipment and process improvements


Qualifications:
  • Bachelor's degree in life sciences, engineering or equivalent experience required.
  • 3 or more years relevant experience in GMP manufacturing environment or laboratory conducting or supporting protein purification methods.
  • Excellent documentation skills and attention to detail.
  • Proficient computer skills with knowledge of spreadsheet and word processing.
  • Strong analytical skills and ability to problem-solve and provide solutions to challenges.
  • Excellent organizational, time management and multi-tasking skills.
  • Ability to meet deadlines and maintain production schedule.
  • Ability to follow written and verbal instruction and work under supervision.
  • Experience with operational excellence tools and methods, preferred.
  • Ability to understand and exercise basic mathematical calculations.
  • Ability and interest working in a fast-paced, high-growth team environment.
  • Ability to lift up to 40lb loads multiple times per shift and carry up to 30 lbs. Must be able to stand, crouch, sit, bend, or stretch for extended periods of time.
  • Ability to work 10 to 12-hour shifts and occasional weekend work.


Reporting Structure:

This position does not have supervisory responsibilities. This position reports to GMP Supervisor-Downstream.

Molecular Templates, Inc. is an Equal Opportunity Employer and offers competitive salaries and benefits.

Molecular Templates Inc https://mtem.isolvedhire.com