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Process Development Downstream Bioprocess Engineer

Employer
Amgen
Location
Rhode Island, RI, US
Start date
Oct 18, 2019

Job Details

Do you want to help shape the future of biopharmaceutical manufacturing? Are you interested in working with a diverse product portfolio of life changing products in a dynamic working environment? Would you like to work with a highly motivated team of process science professionals to positively impact patients' lives?

We have a position available for an Engineer to join our Purification Process engineering team at our Rhode Island Site. The Engineer will be part of a team focused on bioprocess purification process optimization, drug substance manufacturing support and new product introductions. The site operates two multi-product facilities that manufacture a range of innovative biologic and bio-similar medicines. This role will be immersed in all aspects of operations in a commercial bulk drug substance facility.

Responsibilities include:

Apply a fundamental understanding of protein purification unit operations to support commercial manufacturing processes:
  • Large Scale Column Chromatography
  • Tangential flow filtration
  • Normal Flow Filtration
  • Virus Inactivation and Virus Filtration


Use comprehensive understanding of chemical engineering principles for the scale up of unit operations from bench to commercial scale.

Provide technical leadership in solving clinical and commercial drug substance process issues involving equipment, scale, and raw materials. Evaluate process capabilities to develop and implement process and yield improvement opportunities.

Partner with the Process Development laboratories to design experimentation to support process scale up. Perform technical review of data, and author and review GMP documentation.

Execute technology transfer projects to support Amgen Network initiatives. Provide floor support during clinical and validation runs.

The Engineer will be encouraged to keep current on the latest industrial, scientific and regulatory trends to assist in the review and authorship of relevant sections of global regulatory filings. This role provides a great opportunity for significant career development in areas of leadership, teamwork, collaboration, communication and to develop network influence by partnering with colleagues in Process Development, Manufacturing, as well as Quality and Information Systems.

Basic Qualifications

Master's degree

Or

Bachelors and 2 years of Process Development or Operations experience

Or

Associate's degree and 6 years of Process Development or Operations experience

Or

High school diploma/GED and 8 years of Process Development or Operations experience

Preferred Qualifications
  • 1+ years of experience in a Biotech/Pharma Process Development and/or Manufacturing Support role for drug substance manufacturing.
  • Possess basic understanding of regulatory and cGMP requirement
  • Able to apply engineering principles and statistical analysis, including design of experiments, in-order to solve processing issues and evaluate opportunities for process improvements
  • Excellent written and verbal communication
  • Demonstrated ability to work under moderate direction.
  • Able to analyze and interpret data
  • Be a self-starter with the ability to take on several projects at one time


About Amgen

Amgen discovers, develops and delivers innovative human therapeutics. A biotechnology pioneer since 1980, Amgen was one of the first companies to realize the new science's promise by bringing safe, effective medicines from lab, to manufacturing plant, to patient. Amgen therapeutics has changed the practice of medicine, helping millions of people around the world in the fight against cancer, kidney disease, rheumatoid arthritis, and other serious illnesses. With a deep and broad pipeline of potential new medicines, Amgen remains committed to advancing science to dramatically improve people's lives.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Company

We are all different, yet we have this in common: our mission to serve patients. This sense of shared purpose is key to our becoming one of the world’s leading biotechnology companies. It guides us as we continue to launch new medicines and reach millions of patients worldwide.

We live the mission.

We win together.

We thrive on continual challenge.

Our team of 22,000+ scientists and professionals worldwide bring distinct perspectives and experiences to all we do. We leverage our global talent to achieve together—to research, manufacture and deliver ever-better products and greater depth to our mission.

At Amgen, there is a strong correlation between our high level of diversity and performance. Because addressing issues with a wider range of perspectives and approaches leads to more creative problem-solving. Together, we’re transforming the promise of science and biotechnology into therapies that have the power to restore health.

Connect with us to explore how you can Win, Live, and Thrive at Amgen.

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Company info
Website
Phone
805-447-1000
Location
Corporate Headquarters
One Amgen Center Drive
Thousand Oaks
California
91320-1799
United States

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