Research Scientist (CAR Discovery)

Kite, a Gilead Company, is a commercial-stage biopharmaceutical company focused on the development and commercialization of novel cancer immunotherapy products designed to harness the power of a patient's own immune system to selectively target and kill cancer cells. The company is focused on chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered cell therapies designed to empower the immune system's ability to recognize and kill tumors. Kite is based in Santa Monica, CA. For more information on Kite, please visit www.kitepharma.com. Sign up to follow @KitePharma on Twitter at www.twitter.com/kitepharma.

Do you want to make a real difference in the world? Come help us in our quest to cure cancer! Everyone at Kite is grounded by this common goal. Every single day, we seek to establish a direct line between that purpose and our day-to-day work. Join us in our mission!

We are seeking a motivated and creative Scientist to join our team to support CAR discovery and screening efforts. The successful candidate will have a strong record of accomplishments and will be expected to work in a collaborative cross-functional team environment, designing and performing experiments; organizing and analyzing results; and communicating and presenting findings in team meetings and written reports.

Responsibilities include, but are not limited to:

• Design and oversee in vitro functional assays of human T cells
• Work with automation team to increase throughput of in vitro assays
• Work with molecular biology team to design novel gene constructs
• Work with immunologists to develop novel assays
• Culture and engineer mammalian cells
• Perform, monitor, and analyze cell-based assays, cytokine studies, flow cytometry, PCR-based assays
• Effectively communicate plans and results in both oral and written form
• Ability to work in a highly dynamic, collaborative team environment
• Coordination of tasks across multiple projects, demonstrating prioritization and planning
• Interpret and effectively execute experiments in line with project timelines and goals

Requirements:

• PhD Degree in Immunology/Cell Biology/Synthetic Biology/Protein Engineering or related field required
• 0-2+ years industry experience preferred
• Experience with mammalian cell culture and sterile technique
• Experience with flow cytometry and plate-based experiments, including ELISAs
• Experience with protein library design and screening preferred, but not required
• Experience with retroviral and/or lentiviral transgene delivery preferred
• Familiarity with T cell phenotyping, cytotoxicity assays, proliferation, and cytokine/chemokine measurements preferred
• Self-motivated and willing to accept responsibilities outside of initial job description
• Comfortable in a fast-paced company and able to adjust workload based upon changing priorities
• Strong organizational skills and record keeping
• Excellent interpersonal, verbal, and written communication skills are essential in this collaborative work environment

#LI-MO1

#IND123

Kite is a biopharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid, long-term durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered cell therapies designed to empower the immune system's ability to recognize and kill tumors. Kite is based in Santa Monica, CA. For more information on Kite, please visit www.kitepharma.com. Sign up to follow @KitePharma on Twitter at www.twitter.com/kitepharma.

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