R&D Associate, Immune Metabolism

Location
Tarrytown, NY
Posted
Oct 16, 2019
Ref
17548BR
Required Education
Bachelors Degree
Position Type
Full time
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases.

Summary:
We are seeking a highly motivated and experienced research associate to join the Muscle and Metabolism Group to support our discovery and development efforts pertaining to liver-related metabolic diseases. The individual will be responsible for the execution of in vitro and in vivo biological experiments necessary to develop cell-based and animal models for testing of experimental therapeutics and for mechanistic biology studies. The ideal candidate will have in-depth in vitro or in vivo technical expertise, be hardworking, flexible, innovative and able to function effectively in a fast-paced environment. They will also have excellent communication skills and be able to work well in a team.

Responsibilities:

• Strong in vitro and in vivo technical expertise is required. The ideal candidate will have expertise spanning both in vitro and in vivo techniques.

• In vitro technical expertise including, but not limited to:
Tissue culture, transfection, FACS, and in vitro cell-based assay development
Western blotting, chromatography, immunoprecipitation, and ELISA development

• Molecular biology including molecular cloning, mutagenesis, DNA/RNA isolation, qRT-PCR, CRISPR
immunohistochemistry, immunofluorescence staining and in situ hybridization
bright-field, fluorescent, and confocal microscopy and respective image analyses
In vivo technical expertise including, but not limited to:

• Mouse handling, injections (IP, SC, IV), bleeds (tail vein, retro-orbital, submandibular)
oral and IP tolerance tests (glucose, insulin, lipid)

• minor survival surgeries (ie osmotic pump implantation)
major survival surgery experience is an asset

• The candidate will also perform relevant data analysis and interpretation, collate data for presentation or reporting, and present data at group meetings.

• The candidate will be responsible for maintaining accurate and complete laboratory records.

Requirements:

• Minimum of BS/MS + 2+ years' full time work experience is required

• Strong in vitro and in vivo technical expertise is required. The ideal candidate will have expertise spanning both in vitro and in vivo techniques.

• Proficiency in software for data analysis (e.g., DNA sequence alignment, Excel, Prism, FlowJo) and data reporting/presentation (e.g., Word, PowerPoint).

• Ability to multi-task and perform work with a high degree of attention to detail.

• Ability to troubleshoot and intepretate data independently.

• Excellent oral and written communication skills.

• Ability to collaborate productively with different functional groups.

• Strong organizational and timely record-keeping skills.

This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business.

To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.