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Sr. Research Associate

Employer
AnaptysBio, Inc.
Location
San Diego, CA, US
Start date
Oct 15, 2019

View more

Discipline
Science/R&D, Research
Required Education
Bachelors Degree
Position Type
Full time
Hotbed
Biotech Beach

Job Details

Anaptysbio has a new opportunity for a Senior Research Associate to join the Protein Sciences group to support antibody discovery and biophysical characterization activities. This includes using a broad spectrum of analytical, biophysical, and computational tools to characterize antibodies, antigens, and their interactions. The ideal candidate will have passions for protein structure and biophysics, a keen sense of scientific curiosity, and the ability to interact in a matrix environment with members of other groups.

This position reports to the Scientist II, Protein Sciences

Requirements

Education and Experience
  • BA/BS degree in biology, biochemistry, or a related field
  • 5+ years of relevant laboratory experience
  • Strong background in kinetics (i.e. Surface Plasmon Resonance or Octet), especially working with antibodies. Experience with KinExA is a plus.


Knowledge and Competencies
  • Working knowledge of antibody structure/function
  • Experience with a range of analytical tools including all or some of the following techniques: SPR, ELISA, DSC, cIEF, CE-SDS, and DLS
  • Familiarity with protein visualization software (i.e. PyMol, Discovery Studio, etc)
  • Experience with enzyme kinetics is a plus
  • Ability to communicate clearly, and to report and present experimental results and analysis to department colleagues
  • Effective interpersonal skills, strong team player
  • Ability to multitask, prioritize, and function in a fast-paced entrepreneurial environment
  • Able to determine and validate new methods and procedures. Able to perform critical analysis of experimental approach and interpretation of data
  • Demonstrated ability to perform laboratory tasks safely, reproducibly, and efficiently
  • Ability to organize work load and activities to achieve team goals

Company

AnaptysBio is a clinical-stage biotechnology company focused on delivering innovative immunology therapeutics. We are developing immune cell modulators, including two checkpoint agonists in clinical-stage development, for autoimmune and inflammatory disease: rosnilimab, our PD-1 agonist program in a Phase 2 trial for the treatment of moderate-to-severe rheumatoid arthritis; and ANB032, our BTLA agonist program, currently in a Phase 2b trial for the treatment of moderate-to-severe atopic dermatitis. Our preclinical immune cell modulator portfolio includes ANB033, an anti-CD122 antagonist antibody for the treatment of autoimmune and inflammatory diseases. In addition, AnaptysBio has developed two cytokine antagonists available for out-licensing: imsidolimab, an anti-IL-36R antagonist, in Phase 3 for the treatment of generalized pustular psoriasis, or GPP, and etokimab, an anti-IL-33 antagonist for the treatment of respiratory disorders that is Phase 2/3 ready. AnaptysBio has also discovered multiple therapeutic antibodies licensed to GSK in a financial collaboration for immune-oncology, including an anti-PD-1 antagonist antibody (Jemperli (dostarlimab-gxly)), an anti-TIM-3 antagonist antibody (cobolimab, GSK4069889) and an anti-LAG-3 antagonist antibody (GSK4074386).

Our corporate vision is to transform patient health by delivering innovative immunology therapeutics. Find out more about us by following us on Twitter.

 

CONNECT

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Company info
Website
Phone
858-362-6295
Location
10770 Wateridge Circle
Suite 210
San Diego
California
92121
United States

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