Sr. Research Scientist II, Synthetic Biology Technology Development

Employer
Kite Pharma
Location
Emeryville, CA, United States
Posted
Oct 11, 2019
Ref
R0008117
Required Education
Doctorate/PHD/MD
Position Type
Full time
We are seeking a creative, experienced and motivated Senior Scientist to join our team. You will use your background in synthetic biology to develop next generation technologies in cell therapy as you support our efforts focused on solid tumors indications. Specifically, you will be a key contributor in a team focused on advancing our synNotchTM dual tumor antigen sensing platform. The successful candidate will have a strong record of accomplishments and will be expected to work in a collaborative cross-functional team environment, performing experiments, organizing and analyzing results, communicating and presenting findings in team meetings.

Responsibilities include, but not limited to:
  • Employ strategies for the genetic modification of human T cells using next generation chimeric antigen receptors (CAR) and/or T cell receptor (TCR) based technologies.
  • Develop novel protein or RNA based technologies for cell therapy.
  • Design and oversee in vitro functional assays of human T cells.
  • Work with immunologists to engineer therapeutic circuits and proteins to test novel adoptive cell therapy approaches.
  • Effectively communicate plans and results in both oral and written form.
  • Ability to work in a highly dynamic collaborative team environment.
  • Coordination of tasks across multiple projects, demonstrating prioritization and planning.
  • Interpret and effectively execute experiments in line with project timelines and goals.

    Requirements:
  • PhD Degree in Synthetic Biology/Immunology related fields with 3-5 years of industry experience.
  • Direct experience managing Research Associates and/or Scientists.
  • Previous experience engineering mammalian cells preferred but not required.
  • Protein, RNA, and/or circuit engineering background strongly preferred.
  • High proficiency with Golden Gate cloning.
  • Nice to Have: Experience with lentiviral or retroviral transgene delivery. Familiarity with T cell
    phenotyping cytotoxicity assays, proliferation, and cytokine/chemokine measurements.
  • Self-motivated and willing to accept temporary responsibilities outside of initial job description.
  • Comfortable in a fast-paced company and able to adjust workload based upon changing priorities.
  • Strong organizational skills and record keeping.
  • Excellent interpersonal, verbal and written communication skills are essential in this collaborative

work environment.

*LI-RK1

IND-123

Kite is a biopharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid, long-term durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered cell therapies designed to empower the immune system's ability to recognize and kill tumors. Kite is based in Santa Monica, CA. For more information on Kite, please visit www.kitepharma.com. Sign up to follow @KitePharma on Twitter at www.twitter.com/kitepharma.

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