Scientist - Medicinal Chemistry

Thousand Oaks, CA, US
Oct 11, 2019
Required Education
Associate Degree
Position Type
Full time
Amgen is a leading global biotechnology company, with a mission to serve patients around the world. As a science-based, patient-focused organization, we discover and develop innovative therapies to treat serious illnesses. Our medicines have made a dramatic difference in the lives of millions. To underpin our dedication to serve patients, Amgen is hiring in the department of Medicinal Chemistry at our Research and Development facility in Thousand Oaks CA (ATO).

Position Responsibilities

This Scientist role will be part of a creative Medicinal Chemistry group, with responsibilities including (but not limited to) the design, synthesis, and purification of novel compounds for potential clinical drug development. In particular, this role resides within Amgen's Induced Proximity Platform (IPP), which is focused on novel and innovative approaches to modulate intractable targets in diseases using the emerging PROTAC modality.

In this role you will:

Devise and implement state of the art scientific research by conducting laboratory experiments

Plan detailed procedures for defined projects including timelines, milestones, methodological approaches, expected results and necessary resources

Review, analyze and interpret scientific data and results

Provide regular updates, documentation, and/or communication on project results

Collaborate with other scientists and keep current with field of expertise, including literature and technology development

Additional responsibilities may include:

Advising supervisors and colleagues in areas of expertise

Participating in national and international scientific meetings

Providing scientific results that support the generation of publications, patents, or regulatory submissions

Mentoring research associates and laboratory assistants

Basic Qualifications

Doctorate degree OR Doctorate degree completed by June 2020


Master's degree and 4 years of scientific experience


Bachelor's degree and 6 years of scientific experience

Preferred Qualifications

Chemistry degree specializing in organic synthesis

Consistent track record of academic accomplishments (i.e., peer-reviewed publications and/or patents)

Demonstration of good lab practices, with particular attention to safety

Clear understanding of structural determination using NMR and mass spectral techniques as well as knowledge of related purification methods

Understanding of biological and pharmaceutical principles and a working knowledge of the use of structure-based or other computer-aided drug design tools

Knowledge of the application of parallel synthesis techniques to medicinal chemistry

Excellent communication skills (both written and oral)

Amgen focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.

Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.