Principal Innovation Scientist (486)

Location
Milford, Massachusetts, United States
Posted
Oct 09, 2019
Ref
486
Hotbed
Genetown
Required Education
Bachelors Degree
Position Type
Full time
Equal Opportunity Employer

Are you looking to join a new formed innovation team that provides ground-breaking solutions to manufacturing oligonucleotides? Nitto Avecia is the global leader with more than 20 years of experience in the custom manufacturing of oligonucleotide therapeutics used in clinical studies. We are seeking a talent with R&D background in oligonucleotides and is willing to look outside the box. You will be a part to build new groundbreaking platform technologies for our customers. Main focus of this position will be around the chemical synthesizing of the Oligonucleotides and the manufacturing process. You will lead a part of an innovative team that drives results and continuous improvement initiatives.

Purpose of the Position:

The Principal Innovation Scientist is responsible for meeting the innovative chemistry and novel process technology requirements to support research and development projects primarily focused on oligonucleotides.

Key Responsibilities:

He/she develops innovative and new chemistry and process technology around oligonucleotide products by using e.g. a Micro Reactor system to measure all relevant chemical reaction kinetics and process data. The person works closely with team members in analytic and engineering and reports directly to the director of TIIM. He/she develops new procedures and methods for the chemical synthesis and process technology of new and existing oligonucleotide products and scales-up the laboratory results to manufacturing production. In addition, he/she participates and supports TIIM projects in analytic testing, modeling, data analytic and purification technologies.

Supervise/manage staff as needed (1-2 people).

Analyze and review project data, correct errors, and report results for multiple projects to support research and development primarily focused on oligonucleotides

Write technical documents such as test methods, SOPs, protocols, and reports.

Ensure compliance with all applicable cGMP, safety, and regulatory requirements and monitor laboratory compliance.

Communicate professionally with internal and external stakeholders.

Plan, track, execute, and review multiple project team tasks to deliver project results on time.

Job Knowledge Required:

BA/BS/MS with 15+ yrs. of related experience or PhD with 10+ yrs. of related experience

Chemistry and process knowledge around oligonucleotide.

Competency with common synthesis reactions.

Competency in analytic chemistry (HPLC, UPLC, and LC-MS).