Research Scientist, in vivo Target ID

Bristol-Myers Squibb is a global Biopharma company committed to a single mission: to discover, develop, and deliver innovative medicines focused on helping millions of patients around the world in disease areas such as oncology, cardiovascular, immunoscience and fibrosis.

Join us and make a difference. We hire the best people and provide them with a work environment that places a premium on diversity, integrity, collaboration and personal development. Through a culture of inclusion, we create a better, more productive work environment. We believe that the diverse experiences and perspectives of all our employees help to drive innovation and transformative business results.

Research Scientist, in vivo Target ID

The individual hired into this position will join the Discovery Pharmacology and In Vivo Biology Group at Bristol-Myers Squibb in Cambridge, MA and aid the advancement of early stage therapeutic targets at the intersection of tumor genetics and tumor immunobiology. The successful candidate will possess experience in pooled CRISPR screens and mouse tumor models, and leverage these skills to drive in vivo target identification efforts in cancer.

The qualified candidate is a highly motivated, collaborative, and creative individual that possesses the ability to work across a highly matrixed environment to discover new biology and drive new therapeutic target identification and validation in vivo.

Job Responsibilities and Requirements

• A B.S. with a minimum of 7 years, or a M.S. with a minimum of 4 years of post-graduate industry/academic research experience in cancer biology, cellular and molecular biology, or a closely related field, is required. Experience in immuno-oncology research is a plus.

• In collaboration with colleagues in Oncology Discovery New Target Biology, design and execute in vivo pooled genetic screens to identify and validate new targets that modulate immune function and/or tumor cell biology.

• Demonstrated independence in experimental design, execution, data analysis and troubleshooting is required.

• Extensive hands-on experience with cell culture and CRISPR-mediated genome-editing is required, demonstrated experience with pooled CRISPR screens to identify novel targets is highly desired. Required skills include: lentivirus generation and transduction, generation and maintenance of stable cell lines, and general molecular biology techniques.

• Prior experience with mouse handling and tumor models is highly desired.

• Proficiency in utilizing software such as GraphPad, Microsoft office for data analysis and figure generation is required.

• Excellent interpersonal skills with the ability to thrive in a fast-faced and dynamic environment is essential.

• Effective communication of work, plans and progress using written and verbal communication in small and group settings.

• Attention to details with excellent organizational skills, and accurate record keeping is a requirement.

• This position is located in Cambridge, MA. There will be less than 10% travel.

Bristol-Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees the resources to pursue their goals, both at work and in their personal lives.