CAR-T Scientist

South San Francisco, California
Compensation will be commensurate with experience.
Oct 08, 2019
Required Education
Position Type
Full time

Scientist/ Sr. Scientist 

We are creating smarter cell therapies with computer-like logic, enhanced functionality, and greater control.  We are seeking a Senior Scientist to be a integral leader of our CAR-T cell teams generating next-generation cell therapies for cancer.  The successful candidate will not only have a thorough understanding of the CAR T cell field and literature, but be highly experienced in designing, executing, and overseeing well-controlled in vitro and in vivo T cell experiments.    


  • Employ expert knowledge to help lead the company’s efforts to develop next-generation logic gated CAR T cell therapies for treating cancer patients in need
  • Work collaboratively with fellow researchers to plan, execute, analyze, and discuss CAR T cell experimental strategies and data
  • Optimize CAR designs for enhanced T cell function, efficacy, and safety
  • Independently design, execute, and troubleshoot in vitro CAR T cell cytotoxicity and cytokine production assays, using multi-color flow cytometry, Luminex, and IncuCyte instruments.
  • Collaborate with in vivo team to design and oversee in vivo CAR T cell experiments
  • Develop and write experimental protocols and detailed lab records
  • Perform and coordinate data analysis, summaries, and presentations
  • Mentor direct reports and fellow team members in areas of technical expertise
  • Approximately 50% bench work - 50% desk work
  • Promote a positive work environment


  • Ph.D. in immunology, cancer biology, cell biology, gene therapy, or related field
  • >4 years of postdoctoral or industry experience in T cell biology, CAR T cell therapy, or related field
  • Thorough understanding of the CAR T cell landscape, with a working knowledge engineering and assaying in vitro and in vivo T cell activity
  • Proficient in multi-color flow cytometry and FlowJo-based data analysis
  • Demonstrated ability to work independently and as part of a multi-functional team
  • Successful experience in mentoring, training, and leading a small research team
  • Excited by the challenge of working in a dynamic, flexible, and fast-paced start-up company environment
  • You are motivated, detail-orientated, and eager to be part of a positive work environment with other researchers to develop next generation CAR T cell therapies targeting cancer