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Scientist II/Senior Scientist I, Enzymologist

Employer
AbbVie
Location
Lake County, IL, US
Start date
Oct 7, 2019

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Discipline
Science/R&D, Biotechnology
Required Education
Bachelors Degree
Position Type
Full time
Hotbed
BioMidwest, Best Places to Work
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Job Details

We are seeking a highly-motivated protein biochemist/enzymologist, preferably with pharma/biotech experience, to join the Protein Degradation group in North Chicago, IL. This individual should have expertise in ubiquitin-related signaling or targeted protein degradation biology. A proven track record in successfully developing biochemical assays that probe this system is preferred. This individual should enjoy working with innovative technologies in a fast-paced environment.

Key responsibilities

  • Providing expertise in ubiquitin-related signaling and E3 ligase biology
  • Develop innovative strategies to study Protein Degrader engagement with the ubiquitin proteasome system
  • Developed robust in vitro profiling assays that support chemistry efforts in understanding structure-activity relationships
  • Apply novel techniques towards Protein Degrader drug discovery and elucidation of mechanism of action
  • Lead and interact with cross-functional scientific teams
  • Read and apply relevant scientific literature
  • Present research activities at internal and external meetings.


Level and compensation will be commensurate with experience

Education and training

  • B.S (7+ years of experience)., M.S. (5+ years experience) or Ph.D. (0+ years of experience) in Enzymology or Biochemistry


Qualifications

  • Experience and publication track record in ubiquitin-proteasome system and targeted protein degradation biology
  • Proficient at developing robust high-throughput biochemical assays. Preference towards cell-free ubiquitination assays
  • Experience with molecular and cell biology techniques.
  • Experience analyzing data using statistical software programs such as GraphPad PRISM, Microsoft Excel, and Spotfire
  • Motivated, independent, and productive problem solver with a proven ability to advance new scientific understandings
  • Excellent verbal and non-verbal communication skills
  • Ability to work independently, yet works efficiently in teams to achieve objectives
  • Present research activities/results at internal and external meetings, and publish in peer-reviewed journals


Preferred:

  • Industrial experience
  • M.S. 5+ years or Ph.D and 2+ years of experience in Enzymology or Biochemistry


Key Leadership Competencies:

  • Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance.
  • Learns fast, grasps the "essence" and can change course quickly where indicated.
  • Raises the bar and is never satisfied with the status quo.
  • Creates a learning environment, open to suggestions and experimentation for improvement.
  • Embraces the ideas of others, nurtures innovation and manages innovation to reality.

Company

AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women’s health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, and YouTube.

Stock Symbol: ABBV

Stock Exchange: NYSE

Company info
Website
Phone
1-800-255-5162
Location
1 North Waukegan Road
 North Chicago
Illinois
60064
US
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