Investigator II

200+ projects in clinical development. That’s the number of projects that keeps us busy!

At the Biologics Centre of Novartis Institute for BioMedical Research (NIBR), we would like to bring numerous research programs into effective cell and gene therapies on our journey to reimagine medicines! 
We are looking for a motivated and curious scientist to join our team and work on the engineering and development of AAV producer suspension cell lines and vectors at the research and development interface. Our dynamic working environment is a great opportunity to collaborate with the global research teams across the different disease areas, and advance cell and gene therapies into clinic in close interaction with the technical development organization.

We are looking for an Investigator II based in Cambridge, eager to take the responsibility for strategy, planning and execution of the experiments, to enable projects to transition into development and to market.  

What you’ll be doing
Your responsibilities will include, but are not limited to:

• Contribute to strategy, design and development of state of the art AAV packaging and producer suspension HEK cell lines, includes hands-on execution
• Mentoring/Supervising lab associates
• Interfacing with scientist in the research project teams to address target and therapies’ specific needs     
• Testing and screening of cell lines and processes to identify best parameters for transfer to CGTD (CGT Technical Development)
• Interfacing with scientists in the Cell and Gene Therapy Technical Development (CGTD) unit to address process development and manufacturing specific needs 
• Manage the interfaces with other partnering functions like quality and regulatory organization to support project filing throughout clinical development and market 

Job Requirements 

What you will bring to the role: 

• PhD in virology, gene therapy, molecular biology, genetics, or a related field with at least 5 years of laboratory experience
• In-depth knowledge of literature, methodology, and biotech/pharmaceutical industry developments in the field of adeno-associated virus-related gene therapy
• Experience with AAV expression in mammalian cell culture
• Experience with biologics research and development is desired
• Experience or knowledge of regulatory requirements for the generation of documented cell lines
• Excellent oral and written communication and interpersonal skills; 
• Commitment to mentorship and developing the careers of others and yourself
• Self-motivation, enthusiasm, and scientific curiosity

What Novartis can offer you?

There is much more beyond competitive salary, and exceptional benefits which we offer

• An organization that is committed to your development and advancement
• Working in the motivating environment with the latest AAV technologies, and the true pioneers in the field
• Opportunity to translate AAV research advancement into effective therapiesBe a part of a drug discovery and development with the novel biologics class in the established pharma setting

Why consider Novartis?

750 million. That’s how many lives our products touch. And while we’re proud of that fact, in this world of digital and technological transformation, we must also ask ourselves this: how can we continue to improve and extend even more people’s lives? 

We believe the answers are found, when curious, courageous and collaborative people like you and us are brought together in an inspiring environment. Where you’re given opportunities to explore the power of digital and data. 

Where we appreciate your curiosity. Where you’re empowered to risk the failure by taking smart risks, and where you’re surrounded by people who share your determination to tackle the world’s toughest medical challenges. Where we work together to cure the patients.

We are Novartis. Join us and help us reimagine medicine.
The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.