Scientist I/II, CAR-T Cellular Therapy, Discovery

Redwood City, CA, US
Oct 04, 2019
Required Education
Bachelors Degree
Position Type
Full time
In AbbVie Oncology Early Development (OED), we strive to develop a rich and innovative pipeline of transformative cancer therapies by uniquely combining our deep knowledge in core areas of biology with cutting-edge technologies, and working together with our partners - scientists, clinical experts, industry peers, and patients - to discover and develop medicines that drive groundbreaking improvements in cancer treatment.

We are seeking a highly motivated individual to join AbbVie's rapidly expanding cellular therapy group in Redwood City, CA. In this role, you will be responsible for generating antigen-specific CAR-T cells, creation of target antigen positive and negative cell lines and functional biological assays. You will ensure scientific excellence, quality and completeness of key platform initiatives and will collaborate in a multidisciplinary research team in an exciting, fast-paced discovery-oriented environment.
Key responsibilities
  • Working with project teams to coordinate logistics and to conduct in vitro functional studies
  • Conducting studies within timelines to help achieve milestone decisions; anticipating potential hurdles and identifying alternative strategies to minimize impact to project goals
  • Maintaining accurate and timely records of research
  • Developing and delivering scientific presentations and reports for internal meetings
  • Working as part of a highly collaborative interdisciplinary group in an integrated and well-supported research laboratory
  • Reviewing, comprehending and following all SOP's and quality assurance standard pertaining to specific area

Scientist I: Bachelor's Degree or equivalent education with typically 5+ years or a Master's Degree (or equivalent education) with typically 2+ years of experience

Scientist II: Bachelor's Degree or equivalent education with typically 7+ years or a Master's Degree (or equivalent education) with typically 5+ years of experience
  • Practical experience with primary cell culture, T cell functional assays, and molecular biology techniques is required
  • A strong expertise in molecular biology, T cell biology and oncology research experience is desirable
  • Skills include, but not limited to: flow cytometry (FACs), PCR, qPCR, ELISA, Luminex, retroviral/lentiviral based transduction systems, T cell clone generation
  • Background in immuno-oncology research
  • Experience with in vitro mammalian cell culture
  • Proficiency with the software program Prism
Key leadership attributes
  • Builds positive relationships with peers and cross functionally with partners outside of team to enable higher performance
  • Learns fast, grasps the "essence" and can change course quickly where indicated
  • Raises the bar and is never satisfied with the status quo
  • Creates a learning environment, open to suggestions and experimentation for improvement
  • Embraces the ideas of others, cultivates innovation and manages innovation to reality