Scientist I/II, CAR-T Cellular Therapy, Discovery

Employer
AbbVie
Location
Redwood City, CA, US
Posted
Oct 04, 2019
Ref
1906044
Required Education
Bachelors Degree
Position Type
Full time
In AbbVie Oncology Early Development (OED), we strive to develop a rich and innovative pipeline of transformative cancer therapies by uniquely combining our deep knowledge in core areas of biology with cutting-edge technologies, and working together with our partners - scientists, clinical experts, industry peers, and patients - to discover and develop medicines that drive groundbreaking improvements in cancer treatment.

We are seeking a highly motivated individual to join AbbVie's rapidly expanding cellular therapy group in Redwood City, CA. In this role, you will be responsible for generating antigen-specific CAR-T cells, creation of target antigen positive and negative cell lines and functional biological assays. You will ensure scientific excellence, quality and completeness of key platform initiatives and will collaborate in a multidisciplinary research team in an exciting, fast-paced discovery-oriented environment.
Key responsibilities
  • Working with project teams to coordinate logistics and to conduct in vitro functional studies
  • Conducting studies within timelines to help achieve milestone decisions; anticipating potential hurdles and identifying alternative strategies to minimize impact to project goals
  • Maintaining accurate and timely records of research
  • Developing and delivering scientific presentations and reports for internal meetings
  • Working as part of a highly collaborative interdisciplinary group in an integrated and well-supported research laboratory
  • Reviewing, comprehending and following all SOP's and quality assurance standard pertaining to specific area


Scientist I: Bachelor's Degree or equivalent education with typically 5+ years or a Master's Degree (or equivalent education) with typically 2+ years of experience

Scientist II: Bachelor's Degree or equivalent education with typically 7+ years or a Master's Degree (or equivalent education) with typically 5+ years of experience
  • Practical experience with primary cell culture, T cell functional assays, and molecular biology techniques is required
  • A strong expertise in molecular biology, T cell biology and oncology research experience is desirable
  • Skills include, but not limited to: flow cytometry (FACs), PCR, qPCR, ELISA, Luminex, retroviral/lentiviral based transduction systems, T cell clone generation
Preferred:
  • Background in immuno-oncology research
  • Experience with in vitro mammalian cell culture
  • Proficiency with the software program Prism
Key leadership attributes
  • Builds positive relationships with peers and cross functionally with partners outside of team to enable higher performance
  • Learns fast, grasps the "essence" and can change course quickly where indicated
  • Raises the bar and is never satisfied with the status quo
  • Creates a learning environment, open to suggestions and experimentation for improvement
  • Embraces the ideas of others, cultivates innovation and manages innovation to reality