Senior Scientist II, Analytical Chemistry - ARD
Within the Predictive Stability and Structural Elucidation group, part of the global Analytical R&D organization, conceive and implement novel experimental approaches to answer a broad spectrum of scientific questions as they relate to process and degradation chemistry for both drug substance and drug product development. These investigations include: elucidation of unknown chemical structures from complex mixtures using high resolution mass spectrometry and other related techniques, drug impurity/degradant profiling, isolation of unknown drug degradation products, probing studies to determine degradation reaction mechanisms, modeling of accelerated stability data to predict shelf-life. Contribute to project science within multidisciplinary teams, and develop productive collaborations, work processes and communications with other groups across drug product development disciplines.
- Routinely demonstrate scientific initiative and creativity in research or development activities.
- Highly autonomous and productive in performing laboratory research or method development, requiring only minimal direction from or interaction with supervisor.
- Formulate conclusions and design follow-on experiments based on multidisciplinary data.
- Process, interpret, and visualize data to facilitate project team decisions .
- May initiate new areas of investigation that are scientifically meaningful, reliable, and can be incorporated directly into a research or development program.
- Demonstrates high proficiency across a wide range of relevant technologies.
- Maintain a high level of productivity in the lab.
- Present and publish work in high level journals and at conferences.
- Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials, controlled drug and radioactive compounds, GxP compliance, and animal care where applicable.
- Direct mentorship of others.
- Bachelor's Degree or equivalent education and typically 12 years of experience, Master's Degree or equivalent education and typically 10 years of experience, PhD and typically 4 years of experience.
- Hands on experience with HPLC analysis and method development.
- Additional experience with LCMS is preferred Possess thorough theoretical and practical understanding of own scientific discipline.
- Effective writer and communicator of research or other regulatory materials.
- Proven effective written and verbal communication skills and ability to interact effectively with interdisciplinary scientists and engineers.
- High attention to detail, creativity in problem solving, strong interpersonal skills and proven ability to successfully work independently and as part of teams.
- Excellent analytical problem-solving skills. Capable of independently developing and troublesh oot analytical methods.
- Demonstrated hands on experience with laboratory automation hardware and software.
- Thorough understanding of statistics with hands on experience with statistical software packages.
- Ability to work on multiple and simultaneous projects as part of a team in a global, fast-paced, setting where priorities may change quickly