Scientist / Senior Associate Scientist, Formulations Development

Redmond, WA , United States
Oct 04, 2019
Required Education
Position Type
Full time
Located in Redmond WA, SystImmune Inc. is a bio-pharmaceutical company focused on the treatment of cancer through developing novel therapeutic bi-specific, and tri-specific antibodies, as well as antibody-drug conjugates (ADC's). Our objective is to create biologics that work through systematic intervention on the solid tumor micro-environment, to either directly attack the tumor and/or to activate the immune system to attack the tumor. We are a group of highly experienced immuno-oncology scientists utilizing several technology platforms to develop world class advanced antibody-based drug therapies.

Essential Duties and Responsibilities
  • Lead pre-clinical and clinical formulation development and stability study for antibody / antibody drug conjugate;
  • Support research team in candidate optimization, selection and validation;
  • Perform UF/DF, HPLC/UPLC, CE, MFI, Osmolality, viscosity, solubility, DLS, and other biophysical techniques;
  • Experience in process transfer and documentation to support manufacturing in China. Strong communication and writing skills in both Mandarin and English are highly preferred;
  • Write and review Standard Operating Procedures (SOP);
  • Participate in timeline planning and decision-making regarding research and PD priorities of company or department and provide information on feasibility of prospective projects;
  • Other duties as assigned.

Education and Experience
  • PhD + 2 years experience or MS with 5+ years experience in protein sciences or a related department. Industry and/or antibody experience a plus;
  • Experience in high throughput screening and solution protein formulation development;
  • Hands-on experience and trouble-shooting proficiency with HPLC/UPLC;
  • Knowledge of biophysical techniques for protein characterization and stability is a must;
  • Ability to design and execute experiments independently;