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Viral Vector Process Development - Scientist/Engineer, Upstream

Employer
Regeneron Pharmaceuticals, Inc.
Location
Tarrytown, NY
Start date
Oct 2, 2019

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Job Details

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases.

Job Summary:

The Preclinical Manufacturing and Process Development group is looking for a Viral Vector Process Development Scientist/Engineer: Upstream, responsible for upstream development efforts to support manufacturing process development functions. This individual will work as part of a cross-functional team to provide Adeno-Associated Virus (AAV) manufacturing processes and products with the aim of providing treatment to unmet medical needs through gene therapy. This is a growth opportunity that combines the excitement and opportunity of a start-up with the security and institution knowledge gained from working for a larger firm.

Job Responsibilities (Included, but are not limited to):
  • As part of the viral vector process development team, design optimized, characterized and robust seed train and bioreactor processes for the upstream production of viral vectors suitable for future GMP clinical production.
  • Develop protocols for vector production in suspension cell lines.
  • Cross-train on and provide support for analytical and downstream operations.
  • Develop expertise in theory and practice of manufacturing steps and analytical methods.
  • Documents experiments, results, and findings in electronic laboratory notebook; presents work at group and department meetings. Maintain instruments and troubleshoots instrumental/experimental problems.
  • Support of weekend or off-hour experimental and pilot scale work, as required.


Job Requirements:

This position requires a Bachelor's and/or Master's degree in either Chemical Engineering, Biochemical Engineering, Biochemistry, or related field. The extent of the candidate's prior experience will determine the grade of the position. The ideal candidate would have:
  • A strong fundamental understanding of the principles of upstream process development.
  • History of developing upstream steps within bioprocesses.
  • Relevant experience with some of the following systems is preferred: NOVA FLEX, NOVA CDV, Benchtop bioreactors, Single-use bioreactors (50-500 L), Biosafety cabinets, incubators, autoclave, Rockwell RSView32, Finesse TruBio, Pi Historian, JMP, LIMS.
  • Prior experience with producing AAV-based gene therapies is a plus.
  • Excellent interpersonal, verbal and written communication skills.
  • Must have strong initiative and drive to complete challenging tasks and learn new technologies.
  • Must be capable of multi-tasking, working both independently and within a team environment.
  • Job will periodically require short duration physical exertions, including light-medium weight lifting.

Supervisory Responsibility:

• May directly or indirectly lead, guide, and assist Co-op students and interns in conducting research and development, analyzing results and documenting findings. Sets goals, assigns tasks, provides performance management and development.

This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business.

To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Company

Regeneron is a leading biotechnology company that invents life-transforming medicines for people with serious diseases. Founded and led for 30 years by physician-scientists, our unique ability to repeatedly and consistently translate science into medicine has led to seven FDA-approved treatments and numerous product candidates in development, all of which were homegrown in our laboratories. Our medicines and pipeline are designed to help patients with eye disease, allergic and inflammatory diseases, cancer, cardiovascular and metabolic diseases, infectious diseases, pain and rare diseases.
 
Regeneron is accelerating and improving the traditional drug development process through our proprietary VelociSuite® technologies, such as VelocImmune® which produces optimized fully-human antibodies, and ambitious research initiatives such as the Regeneron Genetics Center, which is conducting one of the largest genetics sequencing efforts in the world.

Stock Symbol: REGN

Stock Exchange: NASDAQ

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Company info
Website
Phone
914-847-7000
Location
Corporate Headquarters
777 Old Saw Mill River Road
Tarrytown
New York
10591
United States

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