R&D Specialist

Location
Tarrytown, NY
Posted
Oct 02, 2019
Ref
17835BR
Required Education
Associate Degree
Position Type
Full time
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases.

Summary:
The Bioassay group in the Therapeutic Proteins Department seeks a Research Associate / Specialist to perform in vitro characterization of preclinical and clinical drug candidates in Regeneron's pipeline. Responsibilities will include sample testing to support preclinical development and development of cell-based assays to measure the biological activity of protein reagents and monoclonal antibodies (e.g. cytotoxicity assays and luciferase reporter assays) for transfer to a QC environment. Candidate must be able to work comfortably in a fast-paced, collaborative environment, and be able to work on multiple projects in parallel. The individual will also execute experiments to characterize preclinical antibodies to support regulatory filings. The ideal candidate will have experience with mammalian cell culture, stable cell line generation, luciferase assays, flow cytometry and bioassay automation.
You are joining a collaborative, highly innovative and inspiring environment with extensive resources and access to state of the art technologies. As part of this role you will interact with stakeholders from various departments and through your role and data, you will contribute to development of various clinical programs. The following requirements and responsibilities are required for you to complement our team:

Responsibilities:
1) Mammalian cell culture of adherent and non-adherent cell lines.
2) Characterize and optimize cell-based functional assays using engineered-immortalized cells.
3) Set up and run bioassays for screening and potency measurements.
4) Operate a variety of instruments including but not limited to HyperCyte, Accuri C6
5) cytometer, Cytoflex, ImageXpress micro XL, Victor, Hamilton, Envision Multilabel plate reader, etc.
6) Great attention to details and record keeping.
7) Experience with 384-well automation is a plus.
8) Ability to follow directions, learn new methods and flexibility to changing priorities.
9) Good communication skills, good planning and ability to meet deadlines.
10) Provide regular presentations/verbal updates.
Requirements:
1) Strong aseptic cell culture skills
2) Cell-based potency assays
3) Experience with luciferase based reporters
4) Flow cytometry expertise
5) Experience with Immunofluorescence staining procedures
6) Stable cell line engineering skills

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This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business.

To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.