Research Associate / Senior Research Associate, Microbiology

Location
South San Francisco, CA, United States
Posted
Sep 20, 2019
Ref
4441543002
Discipline
Science/R&D, Research
Hotbed
Biotech Bay
Required Education
Associate Degree
Position Type
Full time
We are seeking a Research Associate / Sr. Research Associate with experience in microbiology and demonstrated ability to perform research in a corporate environment. Working as a key member of the research microbiology group, you will help discover new live biotherapeutic products (LBPs) for a variety of disease indications. The ideal candidate will have expertise in microbiology and molecular biology, be comfortable multitasking in a fast-paced environment, and be a great team player.

Key responsibilities include:
  • Apply microbiology techniques for culturing and analyses of anaerobic and aerobic bacteria.
  • Apply molecular biology techniques including DNA extraction from microbial cultures and biological samples and PCR/qPCR
  • Assist in the implementation of new assays to enhance the discovery capabilities of the microbiome platform
  • Prepare fermentation media and other solutions
  • Assist in small-scale fermentation
  • Keep precise experimental records and enter data into databases
  • Coordinate sample analysis among different experiments
  • Assist in laboratory supplies and equipment ordering
  • Present experimental designs, results and interpretations in visual, oral, and written forms to internal stakeholders
  • Collaborate with cell biologists, immunologists, computational and bioinformatics scientists to design and interpret experiments

Preferred Qualifications:
  • BA/BS in microbiology or related biological science with 2+ years of experience in biotech/pharmaceutical research. Candidates at the senior level should have 5+ years of direct experience
  • Experience working with microbial cultures in an aseptic environment: microbial culture inoculation, transfer and scale up, use of multichannel pipettes and plate reader is essential
  • Experience anaerobic microbes and anaerobic gas chamber is desirable.
  • Experience in working with DNA/RNA NGS samples
  • Ability to independently perform, troubleshoot and interpret experiments
  • Ability to prioritize and deliver results with a strong emphasis on quality, detail, documentation, technical rigor, and timely delivery
  • Highly motivated, proactive, and able to work well in a fast-paced team environment

About Assembly Bio

Assembly Biosciences (NASDAQ: ASMB) is a clinical-stage biotechnology company developing innovative therapeutics targeting hepatitis B virus (HBV) and diseases associated with the microbiome. The HBV program is focused on advancing a new class of potent, oral core inhibitors that have the potential to increase cure rates for chronically infected patients. The microbiome program is developing novel oral live microbial biotherapeutic candidates with Assembly Bio's fully integrated platform, including a robust process for strain identification and selection, GMP banking and production, and targeted delivery to the lower gastrointestinal tract with the GEMICEL ® technology.

We believe our Microbiome platform represents a best in class approach to developing biopharmaceutical agents from live biotherapeutic products. ABI-M201, our lead program in mildly to moderately active ulcerative colitis (UC), is currently in a phase 1b clinical trial. This program is part of a broader collaboration we established with Allergan in 2017 for gastrointestinal programs such as UC, Crohn's disease and Irritable Bowel Syndromes with potential total development and commercial milestones of up to $2.8 billion. Our internal pipeline comprises first in class or best in class live microbial biotherapeutic approaches in areas such as oncology, immune mediated and metabolic disorders, and other areas of high medical need.

We pride ourselves on creating a culture and work environment that is scientifically driven, ambitious, and collaborative. We encourage diversity of thought that leads to great innovation and are looking to add to our dynamic team of great people who are driven to transform the lives of patients.

Assembly Bio is headquartered in Carmel, Indiana, while the R&D headquarters is in South San Francisco. The Company also has a microbiome manufacturing facility in Groton, CT, and offices in China. Assembly Bio has a strong balance sheet having raised approximately $166 million in July 2018. We are positioned well to build the next phase of the Company toward global development and commercialization of our innovative medicines in HBV-cure and the Microbiome.

AAP/EEO Statement
Assembly Biosciences is an Equal Opportunity Employer and prohibits discrimination and harassment of any kind. We are committed to the principle of equal employment opportunity for all employees and to providing employees with a work environment free of discrimination and harassment. All employment decisions are based on business needs, job requirements and individual qualifications, without regard to race, color, religion or belief, national, social or ethnic origin, sex (including pregnancy), age, physical, mental or sensory disability, HIV status, sexual orientation, gender identity and/or expression, marital, civil union or domestic partnership status, past or present military service, family medical history or genetic information, family or parental status, or any other status protected by the laws or regulations in the locations where we operate. We will not tolerate discrimination or harassment based on any of these characteristics.