Scientist II/ Senior Scientist I (Engineer), Downstream, Manufacturing Sciences

Employer
AbbVie
Location
Worcester, MA, US
Posted
Sep 19, 2019
Ref
1905225
Required Education
Bachelors Degree
Position Type
Full time
We are seeking a highly-motivated Scientist (Engineer) to join our Downstream group in the Manufacturing Sciences department at AbbVie BioResearch Center based in Worcester, MA. As part of the Manufacturing Sciences organization, our group leads the downstream process optimization, validation, implementation, continuous improvement and global technical support for late-stage and commercial manufacturing of therapeutic proteins for AbbVie. We also provide manufacturing support and author regulatory filing CMC sections. The candidate should have experience and comprehensive knowledge in process characterization and process performance qualification. The candidate is expected to devise and implement protein purification strategies to solve complex challenges across the AbbVie pipeline.

Key Responsibilities Include:
  • Design, execution, and interpretation of results of process characterization and optimization experimental studies; and the design and documentation of process performance qualification
  • Identify, evaluate, and develop innovative technologies within the field of downstream processing to improve process efficiency, robustness and product quality
  • Lead technology and process transfer to pilot scale and GMP plants; solve technical issues and support GMP manufacturing
  • Participate in cross-functional team and author/review/defend CMC sections of regulatory filings.
  • Author technical reports and validation documents
  • Interact with cross-functional groups (e.g. discovery, process sciences, manufacturing, quality, regulatory)
  • Author peer-reviewed articles and patent. Present original work in conferences.


Position will be hired based on level of experience.
  • BS, MS, or PhD in Chemical or Biochemical Engineering, Biochemistry, or related field with typically 7-10+ years (BS), 5-8+ years (MS), or 0-3+ years (PhD) of relevant experience; pharmaceutical industry experience preferred.
  • Outstanding record of accomplishment in areas of purification bioprocess development, improvement, and validation.
  • Strong written and oral communication skills and the ability to contribute in a multi-disciplinary environment are essential.
  • Interacts well with diverse groups within function and maintains strong working relationships with internal, global, and external collaborators.
  • Demonstrated problem-solving skills and capability to overcome complexed issues.
  • Demonstrated success in coordinating and executing important projects to achieve business unit goals.
  • Must have a "results-oriented" work ethic and a positive, "can-do" attitude with a strong sense of urgency and self-motivated desire to achieve.