Associate Scientist/Scientist: Immunology/Cancer Immunotherapy

Xencor is a clinical-stage biotechnology company developing innovative drugs that mobilize the immune system to target and destroy cancer cells. We are seeking a talented and motivated immunologist to join us in advancing our pipeline of novel bispecific antibodies, cytokines, and other first-in-class immunotherapies. 

 Responsibilities: 

· Establish and conduct in vitro immunological assays to explore mechanisms of action and support development of clinical candidates with optimal pharmacologic properties 

· Support and analyze translational and animal models assessing the efficacy and safety of biologic immunotherapies in preclinical and clinical development 

· Use state-of-the-art high-throughput instrumentation to execute experiments with scientific rigor in a fast-paced, matrixed research environment 

· Work both independently and in close collaboration with other scientists in the immunology group and across all research 

 Qualifications: 

· PhD in immunology or a related field, preferably with several years of relevant postdoc or industry experience 

· Demonstrated research skills in immunology, cell biology, and preferably immuno-oncology 

· Technical expertise in flow cytometry, with proficiency in data analysis using software including FACS Diva, FlowJo, Prism, and Excel 

· Extensive experience in isolation and culture of primary human and mouse cells, including immune cells 

· Broad hands-on experience in immunological techniques including T cell functional assays (e.g., activation, proliferation, target-cell killing, and cytokine responses) 

For consideration, please include a cover letter and resume. 

Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. 

Please note this job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities and activities may change at any time with or without notice.