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Temporary Formulation Development Associate (Full-time)

Employer
Nurix Therapeutics
Location
San Francisco
Start date
Sep 17, 2019

View more

Discipline
Science/R&D, Biotechnology
Required Education
Bachelors Degree
Position Type
Full time
Hotbed
Biotech Bay

Job Details

We are currently seeking an experienced temporary full-time associate to help with analytical chemistry in the formulation laboratory at Nurix Therapeutics. This will include pre-formulation studies, stability studies, support for formulation development, routine dose analysis, and laboratory maintenance. The job is focused on oral dosage forms of novel compounds.

The development associate will work under the guidance of their immediate supervisor and should be self-driven, innovative and thorough in performing a range of novel tasks. A thorough understanding of how to independently perform analytical experiments typical of an oral small molecule formulation development lab is required, while experimental design will remain dynamic across a number of programs in early discovery through clinical development.

Qualifications

Degree in a relevant field (physical sciences or life sciences). Independent, self-motivated and integrates well within a team. Exceptional organizational skills with an ability to work in a high paced team environment to meet deadlines and prioritize work on multiple projects are needed as are excellent oral and written communication skills.
  • Experience in an analytical chemistry or small molecule formulation lab.
  • Experience with analytical sample preparation and analyzing chemical samples by HPLC for assay and purity. (Empower® experience a plus)
  • Experience in running dissolution, stability and physical testing experiments on solid dosage forms preferred.
  • Experience in formulation for preclinical animal models (solutions and suspensions) and solid oral dosage forms (capsules and tablets) a plus.


Fit with Nurix Culture and Values

• Strong team orientation; highly collaborative
• Solutions and results-oriented focus
• Hands-on approach; resourceful and open to diverse points of view

Company

Nurix Therapeutics is a biopharmaceutical company focused on the discovery, development and commercialization of small molecule therapies designed to modulate cellular protein levels as a novel treatment approach for cancer and immune disorders. Leveraging Nurix’s extensive expertise in E3 ligases together with its proprietary DNA-encoded libraries, Nurix has built DELigase, an integrated discovery platform to identify and advance novel drug candidates targeting E3 ligases, a broad class of enzymes that can modulate proteins within the cell. Nurix’s drug discovery approach is to either harness or inhibit the natural function of E3 ligases within the ubiquitin proteasome system to selectively decrease or increase cellular protein levels.

Nurix’s wholly owned pipeline comprises targeted protein degraders of Bruton’s tyrosine kinase, a B-cell signaling protein, and inhibitors of Casitas B-lineage lymphoma proto-oncogene-B, an E3 ligase that regulates T cell activation. Nurix is headquartered in San Francisco, California.

Company info
Website
Phone
415-660-5320
Location
1700 Owens Street
Suite 205
San Francisco
California
94158
US

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