Amgen

Process Development Senior Scientist

Employer
Amgen
Location
Thousand Oaks, CA, US
Posted
Sep 08, 2019
Ref
R-80922
Required Education
Bachelors Degree
Position Type
Full time
Amgen Job Description

Amgen is currently seeking a Senior Scientist in our Drug Product Technologies Department with a background in Protein Biochemistry.

This position will identify current gaps in Amgen's tools and technology to advance our understanding of protein: protein, protein: excipient and protein: surface interactions. Working in a science-based organization, the successful candidate will lead the evolution of our understanding of the molecular drivers of aggregation, solution viscosity, and protein: surface interactions as they pertain to drug product development. This individual will provide unique solutions to these challenging protein interactions. The optimization of protein therapeutics for stabilization towards alternative modes of delivery and storage is of critical importance in the development of human therapeutics. Cross-functional and cross-team collaborations are expected. Experience in developing and implementing emerging technologies is required.

Responsibilities include:

• An opportunity for to develop, advance and apply protein biochemistry/polymer technologies to drug delivery challenges

• Drive continuous improvement in our knowledge of protein behavior through technological innovation and application of experimental findings

• Responsible for development and exploration of new technologies for different modalities such as fusion proteins, mAb fragments, RNA based drugs

• Deliver progress reports, presentations, expectations include both internal and external presentation of scientific data with an eventual external publication/patent track record.

• Participation in global cross-functional teams working effectively in a highly matrixed team environment to enhance our understanding of protein behavior

Basic Qualifications:

• Doctorate degree and 2 years of scientific experience

OR

• Master's degree and 5 years of scientific experience

OR

• Bachelor's degree and 7 years of scientific experience

Preferred Qualifications:

• Advanced degree in Pharmaceutics, Biotechnology, Biochemistry, Physical Biochemistry or related discipline with 4+ years of Post-Doctoral experience in Protein Biochemistry

• Advanced knowledge and hands on experience in Bio-physical and Molecular Biology techniques

• Experience in developing and implementing emerging technologies

• Strong independent problem solving and communication skills

• Demonstrated background in protein characterization, stability and experience in development of parenteral control release delivery systems

• Publication background commensurate with Protein Biochemistry

• Advanced understanding of predictive methods, protein stability and solubility

• Demonstrated background in modeling and prediction of protein: protein interactions, protein: small molecule interactions and protein behavior

• Demonstrated ability to learn and act on dynamic information at a rapid pace

Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology.

Amgen focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.