Bristol-Myers Squibb Company

Research Scientist 1/2

Location
Redwood City, CA, United States
Posted
Aug 24, 2019
Ref
R1517347
Required Education
Bachelors Degree
Position Type
Full time
Bristol-Myers Squibb is a global Biopharma company committed to a single mission: to discover, develop, and deliver innovative medicines focused on helping millions of patients around the world in disease areas such as oncology, cardiovascular, immunoscience and fibrosis.

Join us and make a difference. We hire the best people and provide them with a work environment that places a premium on diversity, integrity, collaboration and personal development. Through a culture of inclusion, we create a better, more productive work environment. We believe that the diverse experiences and perspectives of all our employees help to drive innovation and transformative business results.

Summary

The Research Scientist will join the Mechanistic Disease Discovery Research team within the Oncology Discovery organization at Bristol-Myers Squibb in Redwood City, CA to deliver potential biomarker and mechanism of action data for targets in the IO space.

Responsibilities

The qualified candidate is a highly motivated, interactive, and creative individual that possesses the ability to work across a highly matrixed environment to support progression of IO therapeutic targets. This position will specifically support the identification of potential biomarkers, receptor occupancy, target engagement and pharmacodynamic assays for these targets. Additionally, the position will support mechanism of action studies using primary human tumors and mouse models. The candidate will be expected to effectively collaborate with colleagues in the oncology, protein engineering, translational medicine, biomarker and clinical groups. The successful candidate will demonstrate superb verbal and written communication, and should be capable of presenting scientific results to multidisciplinary teams and key stakeholders.

Qualifications

A B.S. with a minimum of 7 years of experience, or an M.S. with a minimum of 4 years of academic/industrial experience with strong scientific knowledge and research experience in immuno-oncology or immunology is required.

Demonstrated independence in experimental design, execution, data analysis and troubleshooting is required.

Knowledge of assays utilizing human tumor samples and how these are applied to biomarker identification is required.

Hands on experience with a wide range of in vitro cellular immunological assays, including cell culture and functional immune assays is required. Deep familiarity and experience with flow cytometry is critical.

Experience with analysis of bioinformatic data is desired.

Experience with in vivo/ex vivo pharmacology, common procedures including tissue processing is desired. Working knowledge of in-vivo PK, PD and efficacy studies is desirable.

Experience with organoids and/or explant cultures is desired.

Proficiency in utilizing software such as Graph Pad, Microsoft office etc. for data analysis and figure generation is required.

Ability to mentor more junior scientists and colleagues on best practices in the laboratory would be highly valued.

Attention to detail with excellent organizational and record keeping skills is a requirement.

Excellent interpersonal skills with the ability to interact effectively with people, internally and externally is required.

This position is located in Redwood City, CA.

Bristol-Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees the resources to pursue their goals, both at work and in their personal lives.