Manufacturing Associate - Upstream Development

Location
Austin, TX, USA
Posted
Aug 23, 2019
Ref
83577
Required Education
Bachelors Degree
Position Type
Full time
Company Description:

Molecular Templates is a clinical stage biopharmaceutical company focused on the discovery and development of differentiated, targeted, biologic therapeutics for cancer. We believe our proprietary biologic drug platform technology, referred to as engineered toxin bodies, or ETBs, provides a differentiated mechanism of action that may address some of the limitations associated with currently available cancer therapeutics. ETBs utilize a genetically engineered form of Shiga-like Toxin A subunit, or SLTA, a ribosome inactivating bacterial protein, that can be targeted to specifically destroy cancer cells. Additional information about Molecular Templates can be obtained at www.mtem.com.

Position Overview:

Molecular Templates is seeking an experienced and highly-motivated professional to support upstream processing for manufacturing activities. This position will perform functions related to production and manufacturing operations, including routine microbial fermentation, equipment set-up and calibration tasks, media preparation, quality testing, process documentation, and assist in review and development methods and procedures to control or modify the manufacturing process. This position will also aid in identifying continuous process improvement areas. This will require excellent technical, analytical and organizational skills, along with adherence to written and verbal instructions and accurate and timely completion of manufacturing records.

Job Responsibilities will include:
  • Perform protein expression by microbial fermentation. This includes but not limited to: cell culture, cell banking, bioreactor operation, cell plating, cell harvesting, media preparation, equipment cleaning and sterilization, process data recording
  • Conduct limited characterization of metabolic products and protein expression using common laboratory techniques.
  • Complete required documentation in an accurate and timely manner, and adhere to written procedures and regulatory requirements
  • Review and revise established protocols and SOPs related to drug development such as process development, data trending, and optimization of techniques. This may also include developing and optimizing assays, conducting limited literature search of research study protocols and reports, regulatory documents, and other potential resources.
  • Conduct general laboratory duties, including washing glassware, ordering supplies, and maintaining inventory (e.g. media) and basic laboratory equipment
  • Assist with non-complex projects, such as laboratory sanitization and organization or implementation of new instrumentation, as needed


Qualifications:
  • Bachelor's degree in Life Sciences or equivalent
  • Minimum of one (1) year relevant experience in laboratory setting conducting or supporting microbial protein expression
  • Experience in biopharmaceutical industry, required
  • Demonstrated experience and comprehensive knowledge of upstream processing activities, required
  • Excellent written and verbal communication skills
  • Excellent computer skills with knowledge of spreadsheet and word processing
  • Excellent problem-solving and analytical skills applied to investigations
  • Excellent organizational, time management and multi-tasking skills
  • Ability to follow written and verbal instruction and work under supervision
  • Ability to work in a fast-paced, team environment
  • Ability to regularly lift and/or move up to 50 pounds manually or with additional assistance from staff and/or mechanical lifting equipment (e.g. dolly, cart, lift, hand truck, etc.) to a shelf located 4-6 feet in height; Stand for long periods of time; Bend twist, push/pull, crouch, kneel
  • Must possess flexibility to work varying schedules to support operations, such as occasional 12-hour shift or night shift


Reporting Structure:

This position currently has no supervisory responsibilities. This position reports to Director, Upstream Development.

Molecular Templates, Inc. is an Equal Opportunity Employer and offers competitive salaries and benefits.

Molecular Templates Inc https://mtem.isolvedhire.com