Senior Scientist I, Cell Culture, Manufacturing Science

Worcester, MA, US
Aug 21, 2019
Required Education
Bachelors Degree
Position Type
Full time
The Manufacturing Sciences department within the Operation Science & Technology organization leads the optimization, validation, implementation, continuous improvement and global technical support for late stage and commercial manufacturing of therapeutic proteins for AbbVie. We have an exciting opportunity for a Senior Scientist position in the cell culture group within the Manufacturing Sciences department. The position is based in AbbVie Bioresearch Center, Worcester, MA.

Key Responsibilities Include:

  • Responsible for cell culture process development and manufacturing support for late-stage clinical and commercial biologics.
  • Design and execute experiments in support of process characterization, validation and continuous process improvement
  • Interfaces with other functional groups to facilitate efficient technology transfer/scale-up of production processes
  • Identify and drive technical innovations that will contribute to future business developments and improvements
  • Provide technical support for cell culture manufacturing including routine process monitoring/trending and troubleshooting of any process issues
  • Conceive and execute continuous process improvement activities to improve process efficiency, robustness and product quality
  • Contribute to regulatory filings and provide technical leadership for agency inspections and audits
  • Author relevant sections of annual product quality reports and update process trending plans as required
  • Mentor and enhance team performance and to create a scientific climate of excellence to achieve business goals
  • Communicates project goals and updates within and across departments and provide updates on major programs to site management.

  • Bachelor's Degree or equivalent education with typically 10+ years of experience, Master's Degree or equivalent education with typically 8+ years of experience, PhD with 0+ experience necessary.
  • Relevant experience in areas of cell culture process development and scale-up.
  • Demonstrated skills of independent thought and creativity in science and engineering.
  • Demonstrated success in coordinating and executing important projects to achieve business unit goals.
  • Ability to work effectively in a highly collaborative and dynamic environment.
  • Strong sense of urgency, engagement and self-motivated desire to achieve.
  • Must have a "results-oriented" work ethic and a positive, "can-do" attitude.
  • Excellent communication skills and presentation skills expected.

Preferred Qualifications:
  • Proven track record in one or more of the following: media design, cell metabolism, late stage process development, statistical data analysis and predictive modeling, raw material management manufacturing support, process validation, and regulatory submissions.

Key Leadership Competencies:
  • Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance
  • Learns, fast, grasps the 'essence' and can change the course quickly where indicated
  • Raises the bar and is never satisfied with the status quo
  • Creates a learning environment, open to suggestions and experimentation for improvement
  • Embraces the ideas of others, nurtures innovation and manages innovation to reality