Program Director - Health Scientist Administrator

The mission of the National Institute of Neurological Disorders and Stroke (NINDS), The Division of Translational Research (DTR) is to accelerate basic research findings towards patient use for neurological disorders and stroke by providing funding, expertise, and resources to the research community. DTR provides funding and resources (approximately $100 million annually) through grants, cooperative agreements, and contracts to academic and industry researchers to advance early-stage neurological technologies, devices, and therapeutic programs to industry adoption (i.e., investor funding and corporate partnerships). 

DTR offers a variety of programs for Health Scientist Administrators (HSA) that function as either Program Director or Scientific Project Managers.  These positions support the design, implementation, and management of research activities critical to translational challenges in the treatment of neurological disease.  As such, DTR has exciting opportunities for Health Scientist Administrator positions for programs listed below.  If you qualify for any of these positions, a Health Scientist Administrator announcement will open on Friday, August 23, 2019 and close on Friday, August 30, 2019 (7 days).   You can visit to submit your online application.  Note: Another Health Scientist Administrator announcement will launch on September 16; please check back on this posting for that link. 

HSA/Program Director - Cooperative Research to Enable and Advance Translational Enterprises for Biotechnology Products and Biologics (CREATE Bio) program

The CREATE Bio program is dedicated to biotechnology product- and biologics-based therapies, which broadly include modalities such as peptides, proteins, oligonucleotides, gene therapies, cell therapies, and novel emerging modalities.  The program includes two area of focus: 1) Supporting optimization and identification of appropriate therapeutic candidates and 2) Supporting development including IND-enabling studies for candidate therapeutics as well as early-phase clinical trials.  The National Institute of Neurological Disorders and Stroke (NINDS) is seeking candidates to fill the position of Program Director for the CREATE Bio.  In this key role, the Program Director will manage teams of researchers, consultants, contractors, and NIH program staff to advance projects through discovery and development to first-in-human testing. This position will require expert application of program leadership skills in planning, execution and risk management. The Program Director will work within the senior leadership team at the Division of Translational Research to define strategy and implement best practices to advance basic research towards clinical trials. To be minimally qualified for this position, applicants must hold a PhD from an accredited college or university and possess in-depth knowledge of biologics optimization and development process from early discovery to clinical Phase I; significant experience with drug research and development in the pharmaceutical industry or equivalent preferred with leadership experience on cross-discipline drug discovery or development teams; proven leadership and management skills, excellent communication, negotiation and facilitation skills required, both oral and written, and proven ability to interact effectively with senior management, in public forums and within project teams. 

HSA/Scientific Project Manager - Cooperative Agreement Program (CAP) and CREATE Bio

The Scientific Project Manager for the CAP and CREATE Bio program would manage cooperative agreements; develop milestones and critically evaluate progress of assigned projects; coordinate appropriate statistical and regulatory consultant support for advice on project issues; provide comprehensive assessments that would allow for better disbursement and management of funds; explore community needs and potential new opportunities for biologic therapy discovery and development; and attend workshops in support of these potential new opportunities.  They will be part of the Biomarker team and provide support to the Helping to End Addiction Long-Term (HEAL) Initiative Biomarker funding opportunities and pre-application guidance to investigators for this program.  They will be involved in DTR’s strategic planning efforts and will participate in activities that would enhance and benefit the programmatic management of DTR and NINDS.

HSA/Program Director - Epilepsy Therapy Screening Program (ETSP)

This Supervisory Program Director position will lead and supervise the Epilepsy Therapy Screening Program for DTR by organizing and executing workshops that promote collaborative efforts among preclinical, clinical, industry, non-profit & regulatory experts to provide a comprehensive assessment on the acceleration of therapy development for anti-epileptogenesis.  The incumbent will be responsible for managing milestone-driven cooperative agreements, development & progress, budget, changes in scope, & regulatory pathways for the ETSP team.  S/he will establish improved operational efficiencies for ETSP to provide readily available updates on active projects & a new system for generating project reports for participants in the program. The incumbent must also effectively communicate with a variety of audiences to ensure proper communication of programmatic interests & NIH polices/procedures.

HSA/Program Director - Helping To End Addiction Long Term (HEAL) Pain Biomarkers

The incumbent for this position will support the NINDS and HEAL (Helping to End Addiction Long Term) Biomarker Programs that are focused on the development of biomarkers and biomarker signatures to facilitate the development of therapeutics to treat neurological, neuromuscular and pain disorders, which fills a very visible and important unmet need.  As a Program Director, the incumbent will manage a portfolio of biomarker grants and work with Program Directors within NINDS and across NIH to facilitate biomarker development through the management and development of extramural NIH grants, contracts, consortia and workshops. By joining NINDS your individual talents will promote cutting-edge neuroscience research and make a difference in the lives of millions of people in the United States and around the world.  Individuals with experience and/or training in neuroscience, biomarker development, program management (particularly within NIH), clinical research and therapeutics development are particularly encouraged to apply to this position.

HSA/Scientific Project Manager - Helping To End Addiction Long Term (HEAL) Initiative Pre-Clinical Screening Platform for Pain (PSPP)

The incumbent for this position will support the HEAL (Helping to End Addiction Long-term) Initiative, an aggressive trans-agency effort to speed scientific solutions to stem the national opioid public health crisis.  The incumbent will manage a subset of the total portfolio of projects within the new Platform Screening Program for Pain which is committed to identifying promising non-addictive therapies (e.g. small molecules, biologics and/or device) as alternatives to opiate analgesics. The incumbent will be primarily responsible for managing a portfolio of preclinical projects and includes working directly with external participants and external contractors to execute testing potential pain treatments (small molecules, biologicals, and/or devices) in animal models for evaluating analgesic efficacy and side effect liability, including addictive potential. The incumbent will also aid the Program Director with efforts to help build the program & establishing & maintaining collaborations within NINDS & across other participating Institutes. Experience in experimental design, data analysis and interpretation as well as well training in other drug discovery disciplines, such as ADME (absorption, disposition, metabolism and excretion) or medical device preclinical testing, are highly desirable.   

HSA/Program Director - Blueprint Neurotherapeutics Program/ Biomarkers

The incumbent for this position will provide oversight for the NINDS Biomarker portfolio and Project Management for the Blueprint Therapeutics Program (BPN) including coordination for the planning and execution of a portfolio of milestone-driven grants and contracts.  The incumbent will be responsible for all aspects of administration.  They secure and implement scientific advice from Program Directors and apply expertise to define project objectives and execute projects according to deadlines and within budget while overseeing quality control.  The BPN and NINDS Biomarkers programs operate at capacity and this is a key position within NINDS.  

HSA/Scientific Project Manager - Helping To End Addiction Long Term (HEAL) Initiative Translational Devices Program 

The incumbent for this position will support the HEAL Initiative/Accelerate the Discovery and Pre-Clinical Development of Non-Addictive Treatments for Pain / Translating Devices Program, where discoveries will turn into effective devices for pain treatment and for therapeutic and diagnostic use in humans. This position will oversee milestone-driven cooperative agreements in the HEAL Initiative supporting 10 or more institutes across the NIH. The incumbent will be responsible for managing milestone development and progress, budget, changes in scope, regulatory pathway, and will advise HEAL Initiative implementation teams.

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Applicants must be U.S. citizens.

The NINDS is one of the Institutes of the National Institutes of Health, a component of the Department of Health and Human Services.