Team Leader, Cell Therapy Discovery

Location
Durham, NC, United States
Posted
Aug 12, 2019
Ref
1085818
Hotbed
Bio NC
Required Education
Associate Degree
Position Type
Full time
The Team Leader, Cell Therapy Discovery works within the Cell Therapy Research Team, reporting to the Director of Cell Therapy Discovery. The Team Leader manages a team responsible for carrying out research projects contributing to development of Cell Therapy products in accordance with Precisions goals. The Team Leader position is lab and office-based and will share facilities and resources within the Cell Therapy Discovery team.

Essential Duties and Responsibilities

Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions of this position. This list contains the major duties and requirements of the job and is not all-inclusive. Incumbent(s) may be expected to perform role-related duties other than those contained in this document.
  • Design and direct the execution of experiments pertaining to Cell Therapy
    • Coordinate with Director of Cell Therapy Discovery and Senior team members to plan experiments that need to be carried out to achieve Precisions goals for developing T Cell Therapies
    • Hands-on execution of experiments related to T Cell Therapy if required to meet goals of the company and department
    • Coordinate with Research Assistants, Research Associates and Scientists to plan and carry out experiments to achieve Precisions goals for developing Cell Therapies
      • Plan and assign work for direct reports in support of the Cell Therapy teams goals
        • Identify aspects of experiments to be performed by direct reports as part of a larger ongoing experiment
        • Identify areas where self-directed work can be performed and ensure that the appropriate training and support are in place to successfully complete these independent experiments
      • Oversee that work is being correctly performed, analyzed, recorded and reported
    • Report results to Director of Cell Therapy and Senior Management
      • Share new data, file reports as needed
      • Assist in publishing or presenting data as needed
      • Provide data and write-ups to support patent applications and regulatory filings
  • Responsible for training, development and management of direct reports, including setting clear responsibilities and goals, holding regular performance discussions and reviews and identifying training and development opportunities
  • Responsible for championing company initiatives and partnering with other groups at the company to ensure cross-functional alignment
  • Assist in staffing of Cell Therapy Team
    • Serve as Hiring manager for future direct reports
      • Responsible for onboarding new laboratory personnel, managing training of new personnel in basic and advanced laboratory techniques
  • Assist in the translation of Cell Therapy research projects into feasible and commercially viable therapeutic programs
    • Provide timelines and cost analyses relating to the CAR-T production process
    • Meet with potential academic and industry partners to discuss areas of common interest and potential contract work, collaborations and partnerships
  • Represent Precision BioSciences and the Cell Therapy Discovery Group
    • Attend conferences and other meetings outside of Precision BioSciences, presenting data when appropriate
    • Attend meetings with collaborators and potential collaborators and actively participate in research collaborations
    • Present research findings, timelines and plans during regular and ad-hoc meetings
  • Assist in general operation of the Cell Culture facility
    • Coordinate with Operations and Facilities personnel to ensure:
      • Shared resources are utilized appropriately between teams
      • Consumables are ordered and stocked as needed
      • Cells and other reagents are available for experiments as needed
  • Be an example of Precisions Core Values, throughout the work performed and decisions made, leading by example
  • Proactively raise issues and concerns, while bringing solutions to the table whenever possible
  • Be a champion of change, supporting company decisions, helping teams to understand decisions made even if they feel differently
  • Partner with HR on their teams performance management (corrective actions, PIPs, terminations, performance reviews), professional development, employee relations, keeping up to date and communicating company policies and expectations
  • Participate and support company events (speaking, presenting, meetings, trainings, etc.)

Qualifications

The requirements listed below are representative of the knowledge, skill, and/or ability required to perform this job successfully.

Education/Experience:
  • PhD in cellular & molecular biology/immunology with a minimum of 5 years related academic or industry experience and/or training or;
  • MS in cellular & molecular biology/immunology with a minimum of 8 years related academic or industry experience and/or training or;
  • BS in cellular & molecular biology/immunology with 10+ years related academic or industry experience

Required:
  • Management experience required, consisting of managing a minimum of two concurrent direct reports for greater than two years; experience managing larger groups strongly preferred; experience with Matrix Management or hybrid-Matrix a plus
  • Experience with multiparameter flow cytometric analysis and accompanying data analysis software proficiency

Preferred:
  • In-depth knowledge and experience with cell culture and cell-based assays of lymphocyte function, including proliferation, cytotoxicity and cytokine release assays
  • Experience and knowledge of molecular biology techniques, including: PCR, restriction digestion & cloning, primer design, plasmid isolation and analysis, bacterial transformation and screening, extraction of genomic DNA, DNA sequencing and analysis and proficiency with accompanying data analysis software
  • Familiarity and experience with siRNA, shRNA, protein engineering and gene editing
  • Ability to read, analyze and interpret common scientific journals; ability to define problems, collect and analyze data, establish facts and draw valid conclusions; should have knowledge of Microsoft Office software suite
  • Ability to respond to common inquiries or complaints from customers, regulatory agencies ormembers of the business community
  • Ability to apply advanced mathematical concepts such as exponents, logarithms, quadraticequations and permutations
  • Ability to apply mathematical operations to such tasks as frequency distribution, determinationof test reliability and validity, analysis

Travel Requirements
  • This position requires some travel (5-10%), primarily for scientific conferences, meetings with potential partners, training activities.

Location
  • This position is located at the main headquarters located in Durham, NC and is required to physically be and work in the office, in order to be most effective, and at managers discretion.


Precision BioSciences mission and vision is to translate the worlds most powerful genome editing technology into greatly needed products throughout the life sciences, by being the conduit through which the greatest genome engineering challenges are solved. Precisions wholly proprietary ARCUS genome editing platform enables the production of highly specific nucleases that can insert, remove, and modify DNA at essentially any location in a complex genome. Through our ARCUS platform, we are developing genome editing-based products to address critical needs in oncology, genetic disease, agriculture, and beyond. For additional information, please visit www.precisionbiosciences.com

Precision BioSciences provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, disability, genetic information, marital status, amnesty, or status as a covered veteran in accordance with applicable federal, state and local laws. Precision BioSciences complies with applicable state and local laws governing non-discrimination in employment in every location in which the company has facilities. This policy applies to all terms and conditions of employment, including, but not limited to, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation, and training.