Senior Scientist II/III, Cheminformatics

Employer
AbbVie
Location
Lake County, IL, US
Posted
Aug 09, 2019
Ref
1901193
Required Education
Doctorate/PHD/MD
Position Type
Full time
The successful candidate will work as part of a team to develop modern, cutting edge, cheminformatics techniques, and related software, in order to enhance the drug discovery paradigm at AbbVie. Responsibilities will include:

* Develop methods for data mining and statistical analysis of large datasets such as internal compound data and external chemical databases etc.
* Develop methods for archiving and retrieving data on molecular structures, reaction pathways, molecular interactions, and other phenomena.
* Identify chemical property classifications and trends from large databases using mathematical techniques in order to gain insights and subsequently refine and improve next generation drug design cycles.
* Enhance AbbVie's current suite of informatics tools to further drive competitive advantage in cheminformatics and drug design.
* Classify, collaborate, and recommend improvements for AbbVie's overall small molecule screening collections for target based, virtual, DEL, and phenotypic screening.
* Design and develop novel tools for analyses and visualization of chemical, biological, and structural data.

Collaborate closely with discovery scientists globally to enhance the overall CI and drug design platform at AbbVie. Candidates should have world-class credentials in computational chemistry, biology, or relevant areas of computer science and applied mathematics. Candidates are also expected to have a significant track record demonstrating an ability to deliver high-impact results and timely solutions within a team-oriented environment. Excellent research skills and experience in developing and leveraging cutting-edge cheminformatics design are a must, as are strong interpersonal skills, an ability to influence multidisciplinary teams, a strong collaborative work ethic, ability to adapt to changing needs, and the capacity to multi-task to meet key goals. Excellent communication and presentation skills are essential to success in this position.

Position will be hired based on Education and Experience

Requirements:

*BS & 14+ years of experience; MS & 12+ years of experience;PhD and 6+ years of experience in a scientific discipline

*Proficiency with analysis, presentation, and visualization of medicinal chemistry data using commercial software packages (e.g., Spotfire, Pipeline Pilot, Cresset suite of tools, and Schrodinger suite of tools etc.).

Preferred:

*PhD in Chemistry, Medicinal Chemistry or Computational Chemistry
*Pharmaceutical industry experience
*Working knowledge of Oracle, web technologies (Angular.js, Node.js, D3.js, HTML5, REST or other)
*Experience developing or working with Cloud-based technologies such as Amazon Web Services .