Senior Scientist I/II, Cheminformatics

Employer
AbbVie
Location
Lake County, IL, US
Posted
Aug 09, 2019
Ref
1901196
Required Education
Doctorate/PHD/MD
Position Type
Full time
The successful candidate will work as part of a team to develop modern, cutting edge, cheminformatics techniques, and related software, in order to enhance the drug discovery paradigm at AbbVie. Responsibilities will include:
  • Develop methods for data mining and statistical analysis of large datasets such as internal compound data and external chemical databases etc.
  • Develop methods for archiving and retrieving data on molecular structures, reaction pathways, molecular interactions, and other phenomena.
  • Identify chemical property classifications and trends from large databases using mathematical techniques in order to gain insights and subsequently refine and improve next generation drug design cycles.
  • Enhance AbbVie's current suite of informatics tools to further drive competitive advantage in cheminformatics and drug design.
  • Classify, collaborate, and recommend improvements for AbbVie's overall small molecule screening collections for target based, virtual, DEL, and phenotypic screening.
  • Design and develop novel tools for analyses and visualization of chemical, biological, and structural data.
  • Collaborate closely with discovery scientists globally to enhance the overall CI and drug design platform at AbbVie.


Candidates should have world-class credentials in computational chemistry, biology, or relevant areas of computer science and applied mathematics. Candidates are also expected to have a significant track record demonstrating an ability to deliver high-impact results and timely solutions within a team-oriented environment. Excellent research skills and experience in developing and leveraging cutting-edge cheminformatics design are a must, as are strong interpersonal skills, an ability to influence multidisciplinary teams, a strong collaborative work ethic, ability to adapt to changing needs, and the capacity to multi-task to meet key goals. Excellent communication and presentation skills are essential to success in this position.

A working knowledge Oracle is an advantage as is experience with web technologies (Angular.js, Node.js, D3.js, HTML5, REST or other). Prior experience developing or working with Cloud-based technologies such as Amazon Web Services would be an advantage also.

Basic:

*BS & 10+ years of experience; MS & 8+ years of experience; PhD and 0+ years of experience

*Proficiency with analysis, presentation, and visualization of medicinal chemistry data using commercial software packages (e.g., Spotfire, Pipeline Pilot, Cresset suite of tools, and Schrodinger suite of tools etc.)

Preferred:

*PhD in Chemistry, Medicinal Chemistry or Computational Chemistry with Industry experience

*A working knowledge of Oracle and web technologies (Angular.js, Node.js, D3.js, HTML5, REST or other)
*Prior experience developing or working with Cloud-based technologies such as Amazon Web Services