Bristol Myers Squibb Company

Senior Research Investigator I

Cambridge, MA, United States
Aug 09, 2019
Required Education
Position Type
Full time

The Senior Research Investigator I at Leads Discovery and Optimization (LDO) will join a team located in Cambridge, Boston to develop and transfer high throughput assays for target ID and Validation, hit identification and Lead optimization. The group will work in close proximity to Oncology Biology, Translational Medicine, and Molecular Discovery Technology at Cambridge with a mission to discover and develop innovative Immuno-oncology and Oncology pipelines. The qualified candidate is a highly motivated, interactive, and creative individual that possesses substantial experience in supporting target ID, HTS screening and Lead Evaluation. The ideal candidate should effectively collaborate with colleagues in the oncology discovery group with a goal to apply Biochemistry and enzymology techniques. In addition, this candidate will be included in Drug Discovery working groups and support lead optimization efforts at CAM site. The successful candidate will demonstrate clear and professional verbal and written communication, capable of presenting scientific results to multidisciplinary teams and taking a strong leadership role in the matrix organization cross Discovery functions including LDO. The candidate will develop external partnerships/collaborations to advance CRISPR technology together with the core team in NJ. This individual will demonstrate the ability to contribute to various projects outside of his/her own, and collaborate with stakeholders from all relevant functions


A Ph.D. degree with 5+ years post-doctoral experience or relevant experiences in cancer biology and closely related field

A proven track record in the field of High throughput screening by publication record

Demonstrated ability to design in vitro assays and flowcharts to identify and optimize drug candidates; compound screening testing tree, high triage assay development and key technical skills include Biochemistry techniques, enzyme kinetics and label free technology and lab automation, protein-protein interaction both on cell free and cell bases systems.

Excellent interpersonal skills with the ability to interact effectively with people, internally and externally

Excellent oral and written communication skills

Able to effectively present scientific data and concepts to international standards

Familiar with HT screening technologies platforms

Strong ability to mining and handle large data set.