Bristol Myers Squibb Company

Senior Research Investigator I

Cambridge, MA, United States
Aug 09, 2019
Required Education
Position Type
Full time
Bristol-Myers Squibb is a global Biopharma company committed to a single mission: to discover, develop, and deliver innovative medicines focused on helping millions of patients around the world in disease areas such as oncology, cardiovascular, immunoscience and fibrosis.

Join us and make a difference. We hire the best people and provide them with a work environment that places a premium on diversity, integrity, collaboration and personal development. Through a culture of inclusion, we create a better, more productive work environment. We believe that the diverse experiences and perspectives of all our employees help to drive innovation and transformative business results.


The Senior Research Investigator I at Leads Discovery and Optimization (LDO) will join a team located in Cambridge, Boston to develop and transfer high throughput assays for target ID and Validation, hit identification and Lead optimization. The group will work in close proximity to Oncology Biology, Translational Medicine, and Molecular Discovery Technology at Cambridge with a mission to discover and develop innovative Immuno-oncology and Oncology pipelines. The qualified candidate is a highly motivated, interactive, and creative individual that possesses substantial experience in studying tumor biology and genetics, especially with hands-on experience with the CRISPR technology. The ideal candidate should effectively collaborate with colleagues in the oncology discovery group for target ID and target validation with a goal to apply CRISPR technology to the functional genomic screening. In addition, this candidate will be included in Drug Discovery working groups and support lead optimization efforts at CAM site. The successful candidate will demonstrate clear and professional verbal and written communication, capable of presenting scientific results to multidisciplinary teams and taking a strong leadership role in the matrix organization cross Discovery functions including LDO. The candidate will develop external partnerships/collaborations to advance CRISPR technology together with the core team in NJ. This individual will demonstrate the ability to contribute to various projects outside of his/her own, and collaborate with stakeholders from all relevant functions. S/he will keep up-to-date in the literature related to his/her field, act as an expert resource in his/her scientific field and in related disciplines, and propose new therapeutic targets. This position is located in Cambridge, MA, reporting to the LDO site leader at CAM.


A Ph.D. degree with 5+ years post-doctoral experience in cancer biology and genetics or a closely related field

A proven track record in the field of cancer biology and genetics, as evidenced by publication record

Demonstrated ability to design in vitro and in vivo systems, assays and flowcharts to identify and optimize drug candidates; key technical skills include proficiency in CRISPR, functional genomic screening and complex cellular assay development.

Excellent interpersonal skills with the ability to interact effectively with people, internally and externally

Excellent oral and written communication skills

Able to effectively present scientific data and concepts to international standards

Familiar with HT screening technologies platforms

Bristol-Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees the resources to pursue their goals, both at work and in their personal lives.