Scientist II/ Senior Scientist I, Tau Biology (Cell or Neuropharmacology)

Cambridge, MA, US
Aug 09, 2019
Required Education
Bachelors Degree
Position Type
Full time
AbbVie has established the Foundational Neuroscience Center (FNC) in Cambridge, MA to investigate the fundamental biological mechanisms and to develop therapeutic interventions for neurodegenerative disorders such as Alzheimer's and Parkinson's diseases. The Tau Biology group is seeking a highly motivated applicant with prior experience and expertise in cell biology and molecular neuroscience for target validation and assay development in neuroscience. The Scientist will support a project leader in performing molecular and multiplexed image-based screening studies to look at synapse biology in neurodegenerative disease and discover small molecules/biologics interfering with tau aggregation in neurons.

Key Responsibilities Include:
  • Perform research in a dynamic and collaborative environment
  • Experience in neural activity, cell signaling or neuropharmacology
  • Work efficiently to meet deadlines, well with team members, and contribute to a healthy and fast-paced environment.
  • Excellent communication - both in writing and presenting results with direct report and team, analytical, and interpersonal skills.
  • Read and apply relevant scientific literature

Position will be hired based on level of experience.
  • Bachelors, Masters or PhD in Neuroscience, Cell or Neuropharmacology, with typically 7+(BS), 5+ (MS) or 0+ (PhD) years of experience.
  • Proficiency with cell biology, molecular, microscopy methods, cellular assays for target validation and high throughput screening.
  • Expertise in molecular neuroscience fields such as neuronal activity, synapse biology, neuropharmacology, learning and memory.
  • Experience in primary neuronal culture. Human iPSC-derived neuron is a plus but not required.
  • Experience with super-resolution, high - content, high throughput using robotic-assisted imaging is a plus but not required.
  • Familiarity with plate readers and/or high content imaging. Familiarity with neuroanatomy is plus but not required.
  • Comfortable using programs such as Microsoft, PowerPoint, Google Docs, Microsoft Excel
  • Highly motivated, detailed oriented, curious of the science, and desire to learn to novel neuroscience techniques.
  • Demonstrate critical thinking, independence, clear scientific writing & verbal communication skills and precise record keeping
  • Strong organizational skills that facilitate planning, multitasking and working within timelines.