Research Associate/Scientist

Location
San Francisco, California, US
Posted
Aug 06, 2019
Ref
112585065
Hotbed
Biotech Bay
Required Education
Bachelors Degree
Position Type
Full time
Overview

The Gladstone Institutes is a renowned center of excellence focused on using science to overcome disease. We are an independent, not-for-profit research organization affiliated with the University of California San Francisco and located in an award-winning building at the Mission Bay Campus. Our science contributes to the health and wellbeing of people around the world through research in disease-focused neuroscience and the development of novel therapeutics in this and other disciplines. Home to notable leaders in science and biomedicine, Gladstone provides an ideal environment for those seeking to maximize and fully leverage their potential. Consider Gladstone and make a real difference in human health.

Responsibilities

Opportunity:

Are you a neurobiologist with an interest in drug development for neurological or psychiatric disorders and would like to contribute to this important area in an intellectually stimulating, interdisciplinary academic environment? The Gladstone Institute of Neurological Disease at San Francisco's burgeoning Mission Bay Campus could offer you outstanding opportunities to pursue this goal and improve the lives of people around the world. Depending on level of experience, the successful candidate will lead or contribute to the identification and optimization of novel small-molecule drugs and biologicals in collaboration with innovative neurobiologists and experienced CROs.

The qualified candidate is a highly motivated, interactive, and creative individual with the ability to work in a multidisciplinary environment to advance preclinical drug development programs from target identification/validation through IND enabling activities. The successful candidate will also have exceptional verbal and written communication and the capability to effectively present scientific results to key stakeholders.

Requirements

Qualifications

Position Requirements:
  • A B.S. or an M.S. degree with several years of experience in neurobiology and drug discovery. Demonstrated independence in experimental design, execution, data analysis and troubleshooting.
  • Knowledge of small molecule preclinical drug development, including knowledge of designing and refining assays to identify and optimize drug candidates.
  • Hands-on experience with a wide range of cell-based and biochemical assays, including primary neuronal culture, western blotting, ELISA/MSD, reporter assays, siRNA/shRNA knockdown and qPCR.
  • Experience with in vivo pharmacology, including working knowledge of in vivo PK, PD and efficacy studies.
  • Proficiency in utilizing software such as Graph Pad and Microsoft office for data analysis and figure generation.
  • Knowledge of statistics and experience with advanced bioinformatics tools.
  • Experience with high-throughput screening equipment and robotics.
  • Attention to detail with excellent organizational and record keeping skills.
  • Outstanding interpersonal skills: ability to effectively interact with internal colleagues as well as external collaborators.


Title and salary will be commensurate with education and experience.

PI112585065