Eli Lilly and Company

Post Doctoral Research Scientist- FDE - Oncology Translational Research

Indianapolis, IN, United States
Aug 05, 2019
Required Education
Position Type
Full time
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 39,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.


Are you looking to make a significant difference by contributing to the search for a cure for pediatric cancer? If so, this might be a right role for you where you will be working in an internationally recognized consortium co-led by Lilly and the University of Heidelberg/DKFZ to identify promising drugs for children with cancer. Oncology Translational Research at Eli Lilly and Company is committed to developing innovative, game-changing therapies for the treatment of pediatric cancer.

We are seeking an ambitious post-doctoral scientist with exceptional communication skills to contribute to high visibility translational research projects. Your work will contribute to the development of a world-class preclinical pediatric testing platform. In this role, you will:
  • Support the ITCC-P4 Pediatric Preclinical Proof-of Concept Platform (https://www.itccp4.eu), an IMI2 project (https://www.imi.europa.eu/about-imi) funded by the EU and European Federation of Pharmaceutical Industries and Association.
  • Have significant interaction with the ITCC-P4 consortium, with an emphasis on supporting work packages involved with drug target prioritization/actionability (WP2), model development and characterization (WP3), and drug testing (WP5) and biomarker discovery.
  • Advance the molecular mechanism of action for novel compounds in clinical development; ultimately inform future clinical trials and patient selection strategies by understanding the sensitivity and resistance to small molecule inhibitors across a panel of well-characterized pediatric patient derived xenograft models and pediatric organoids.
  • Work closely with consortium colleagues across the EU as well as travel to EU as needed.
  • Identify areas of key need across clinical development and champion creative solutions to address those needs. Maintain external awareness and learning to benefit the organization.
  • Present findings at international conferences and publish in high quality peer-reviewed journals.

Basic Qualifications
  • PhD in life science related discipline.
  • Strong background in the biology of cancer or related area.

Additional Skills/Preferences

If you are described with these skills, you could be a great fit for the role:
  • Self-directed and highly motivated individual who wants to learn new techniques while continually pursuing research and publication goals.
  • Exceptional communicator (oral and written) with national and international presentation experience, along with strong publication record.
  • Proficient in data analysis and reporting (PRISM, Excel, Powerpoint, Photoshop, Spotfire, etc.).
  • Experienced with mammalian cell culture; 3-dimensional cell culture techniques.
  • Experienced with molecular biology and protein-level analysis.
  • Prior work or knowledge of preclinical cancer in vivo model experience.
  • CRISPR experience is a plus.
  • Targeted protein degradation experience desirable but not necessary.

Additional Information
  • This position is not permanent. It is for a fixed duration of two years with potential to extend annually for up to 4 years.
  • Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.