Eli Lilly and Company

Principal Research Scientist-Neurodegeneration

Indianapolis, IN, United States
Aug 05, 2019
Required Education
Position Type
Full time
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 39,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world. #WeAreLilly


Lilly Neuroscience is seeking an experienced scientist to join the Neurodegeneration team to facilitate its mission of discovering novel medicines for the treatment of Alzheimer's disease, Parkinson's disease, and other related neurodegenerative conditions. Do you have a strong background in performing/designing in vitro and in vivo studies? Have you developed or optimized biochemical assays required for the evaluation of neurodegenerative studies in vivo? You will lead a laboratory focused on developing small molecule therapeutics in close collaboration with other Neurodegeneration laboratories and Lilly's chemistry and biotherapeutic engineering divisions. An important focus for you will be the investigation of the role of misfolded proteins (tau/alpha-syn) across multiple disease states. Additionally, you will have access to many technical specialty groups within Lilly to facilitate your research. You should possess a deep understanding of the pathophysiological processes that underlie neurodegenerative conditions such as Alzheimer and Parkinson's diseases. Are you a strong leader that maintains excellent communication and organizational skills? Lilly has a proud record of drug development for Neurodegenerative diseases that has been led by multiple accomplished scientists.You could be a part of this team.
Key Objectives/Deliverables:
  1. Lead a discovery laboratory with multiple associate scientists
  2. Design and execute preclinical in vivo and in vitro studies for small molecule inhibitors and novel modalities
  3. Perform discovery studies to elucidate novel targets and build internal expertise
  4. Lead multi-disciplinary teams for preclinical development of therapeutics and contribute as an integral team member for clinical development (discovery through full clinical implantation)
  5. Become an internal and external leader with vision for the field of neurodegenerative diseases

Basic Qualifications
  • PhD and/or MD in Biochemistry, Pharmacology, Cell Biology, or a related field with at least 5 years of relevant academic or industry experience.

Additional Skills/Preferences
  • Industry experience preferred
  • Strong publishing record in the field of neurodegenerative diseases.
  • Deep understanding of assay development
  • Deep understanding of Neurodegeneration literature
  • Strong communication/presentation/leadership skills

Additional Information
Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.