R&D Associate -Analytical Chemistry

Tarrytown, NY, United States
Aug 05, 2019
Required Education
Associate Degree
Position Type
Full time
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases.

We are looking for a highly motivated R&D associate with experience in protein mass spectrometry to join the Analytical Chemistry group of Regeneron located at Tarrytown, NY. This role will work in a state-of-the-art mass spectrometry lab and provide biochemical characterization of therapeutic protein drug candidates to support different stages of drug development, from early-stage candidate selection to late-stage regulatory submission. This role will also have opportunities to develop innovative mass spectrometry technologies to support Regeneron R&D programs in the context of multidisciplinary project teams.

This role will primarily be involved in developing and executing state-of-the-art mass spectrometry and its related technologies for the analytical characterization (e.g., intact mass analysis and peptide mapping) of therapeutic proteins (e.g., monoclonal and bispecific antibodies) to support drug development activities at all stages (e.g., INDs, BLAs, comparability studies, stability studies, cell line development, process development, and formulation development), with a primary focus on supporting early stage drug candidate characterization and lead candidate selection.

This role will also be involved in developing innovative mass spectrometry technologies to support R&D programs.

The responsibilities of this role may include, but are not limited to:
  • Develop LC/MS based analytical methods to support the development of monoclonal antibody-based therapeutic proteins;
  • Conduct analytical experiments on therapeutic proteins, and analyze mass spectrometry data to elucidate the quality attributes of therapeutic protein candidates and/or products;
  • Perform analytical method qualification to support late-stage therapeutic protein development programs;
  • Document experiments, results and findings in electronic laboratory notebooks; present work at the group and project meetings; participate in the writing of technical reports, SOPs, and analytical method protocols, etc.
  • Provide data in a quality presentation form (graphs, figures, tables, etc.) to support regulatory submissions and peer-reviewed publications;
  • Participate in the general lab and instrument maintenance.

  • B.S. or M.S. degree in Chemistry, Biochemistry, Pharmaceutical Sciences (or related disciplines). 3-8 years with a BS degree or 0-5 years of post-graduate experiences in protein mass spectrometry.
  • Knowledge and hand-on experience in LC/MS based protein, peptide and PTM analysis
  • Intact mass analysis or peptide mapping skills experience is preferred
  • Strong written and verbal communication skills and excellent interpersonal skills
  • Ability to learn new technologies and solve problems
  • Ability to work in a team environment

This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business.

To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.