Research Associate II/Sr Research Associate , Analytical Development

Aug 02, 2019
Required Education
Associate Degree
Position Type
Full time
Good things are happening at Omeros!

Come join our CMC Omeros Team!

This position will support the development and commercialization of antibody therapeutics. The Research Associate will be responsible for the testing of in-process and finished product samples in the Analytical development laboratory. The candidate will have hands-on experience and familiarity with the analytical testing of proteins, including experience with analytical test method development and troubleshooting. This position will play a significant role in supporting the biophysical and biochemical characterization of monoclonal antibody programs at Omeros.

Who is Omeros?

Omeros is a commercial-stage biopharmaceutical company committed to discovering, developing and commercializing small-molecule and protein therapeutics for large-market as well as orphan indications targeting inflammation, complement-mediated diseases and disorders of the central nervous system.

The company's drug product OMIDRIA® (phenylephrine and ketorolac intraocular solution) 1% / 0.3% is marketed in the U.S. for use during cataract surgery or intraocular lens (IOL) replacement to maintain pupil size by preventing intraoperative miosis (pupil constriction) and to reduce postoperative ocular pain. In the European Union, the European Commission has approved OMIDRIA for use in cataract surgery and other IOL replacement procedures to maintain mydriasis (pupil dilation), prevent miosis (pupil constriction), and to reduce postoperative eye pain.

Omeros has multiple Phase 3 and Phase 2 clinical-stage development programs focused on: complement-associated thrombotic microangiopathies; complement-mediated glomerulonephropathies; Huntington's disease and cognitive impairment; and addictive and compulsive disorders. In addition, Omeros has a diverse group of preclinical programs and a proprietary G protein-coupled receptor (GPCR) platform through which it controls 54 new GPCR drug targets and corresponding compounds, a number of which are in preclinical development. The company also exclusively possesses a novel antibody-generating platform.

What are your job responsibilities?

  • Analytical method testing of proteins therapeutics
  • Monitoring and tracking of laboratory test results
  • Troubleshoot typical method and equipment challenges
  • Write standard test methods, technical reports summarizing analytical data, and qualification reports
  • Reviews work performed by department staff for accuracy and completeness
  • Assists in investigations involving data generated internally and by CROs / CMOs
  • Ensures laboratory equipment is calibrated and maintained in proper working order to enable compliance with relevant regulations.
  • BS or MS degree in Biochemistry, Biology, or a related field with 2+ years of biotechnology and/or pharmaceutical industry experience
  • Experience in testing and using various analytical methods used to test and characterize protein therapeutics, including chromatography-based (SEC, Reverse Phase, CEX, etc.) and/or CE-based (CE-SDS, cIEF, icIEF) methods
  • Experience with troubleshooting and optimizing methods
  • Experience with routine lab equipment and methods, including preparing buffers, measuring pH, UV absorbance, quantifying particulates, etc.
  • Strong understanding of technical principles of chromatographic and/or electrophoretic methods
  • Demonstrated problem solving and multi-tasking capabilities
  • Capable of interpreting data and communicating and presenting results to peers and management
  • Demonstrated written and verbal communication skills with peers and management
  • Demonstrated ability to build and maintain positive and collaborative relationships across functional areas and with management
  • Detail oriented, proactive, and self-motivated
  • Must have the ability to build and maintain positive and collaborative relationships with management and peers
  • Excellent written and verbal communication skills required
  • Must display strong analytical and problem-solving skills
  • Attention to detail required
  • Intermittent physical activity including bending, reaching, pushing, pulling, or lifting up to 40 lbs.
  • May encounter prolonged periods of sitting
  • This position requires working with and near hazardous material
Omeros is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to status as a protected veteran or a qualified individual with a disability, or other protected status such as race, religion, color, national origin, sex, age, marital status, or any other factor determined to be unlawful by federal, state, or local statutes.

It is our policy to provide reasonable accommodation to anyone with a disability who needs assistance completing the job application process. If you need assistance, you can either send an e-mail to or contact Omeros, asking for Human Resources, at (206) 676-5000.