Scientist, Biomarker Development (Opthalmology)

South San Francisco, CA
Jul 26, 2019
Required Education
Position Type
Full time

Join a Team that Lives to Improve Lives

People come to Genentech from across disciplines and across the world to solve our most challenging medical conditions. You’ll find inspiration in our passion for biotechnology, our purpose to positively impact the lives of millions of patients and our dedication to our people. Joining Genentech means being part of a tradition of inquiry that will change the world. It means embracing our failures as much as our successes. It requires a willingness to look beyond the edge of what's possible. And a focus on doing the day-to-day work that makes great science happen. 

The following opportunity exists in our South San Francisco, CA headquarters:

Scientist, Biomarker Development (Ophthalmology)



The department of OMNI Biomarker Development leads biomarker efforts for Phase I through Phase III clinical trials to support novel therapeutics for unmet medical needs.  We use relevant pharmacodynamic biomarkers to evaluate target-engagement and mechanism of action as well as diagnostic biomarkers to guide patient selection.  Our department is responsible for developing biomarker strategies, designing and implementing biomarker measurements, and interpreting biomarker results.  Biomarker team leaders within the department provide scientific leadership for biomarkers for clinical trials ranging from early proof-of-concept through global Phase III and post-launch.  We are currently seeking a highly-motivated scientist to focus on Ophthalmology projects.



The primary responsibility for this individual will be the discovery of novel biomarkers using retinal imaging for implementation in clinical trials for retinal diseases.  This individual will also serve as the biomarker representative on cross-functional project teams and may lead biomarker sub-teams that integrate all biomarker activities for projects in Development. 

Success in these responsibilities requires a thorough understanding of disease and drug target biology, fluency with retinal imaging software and analysis tools, a pragmatic approach to integrating biomarkers into clinical trials, and ability to plan and deliver results according to timelines.   Collaboration with our clinical imaging group and other partners within the company is also essential.

Effective communication is expected and will include presentations at cross-functional teams, internal review committees, and external conferences.  In addition, the individual is expected to contribute to the scientific community by publishing results in high quality journals.

Who You Are

• PhD with 3+ years of post-doc/industry experience in Neuroscience or Ophthalmology.

• Expertise in preclinical and/or clinical retinal imaging (OCT, FA, FAF, etc.).

• Familiarity with emerging image analysis techniques (machine learning, automated segmentation, etc.) and imaging technologies.

• A record of high quality research as demonstrated by publications in top tier journals and external presentations.

• Excellent communication skills and the ability to work on interdepartmental project teams.

• Familiarity with the cellular/molecular pathways that contribute to retinal disease.

• Experience in drug-development (e.g. involvement in clinical practice, clinical trials, or retinal imaging reading centers).

• Applicants with additional experience are encouraged to apply.

A Job with Benefits Beyond the Benefits

A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

The next step is yours. To apply today, click on the "Apply online" button.

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