Scientist - Protein Technologies
- Employer
- Amgen
- Location
- South San Francisco, CA, US
- Start date
- Jul 23, 2019
View more
- Discipline
- Science/R&D, Biotechnology
- Required Education
- Bachelors Degree
- Position Type
- Full time
- Hotbed
- Biotech Bay, Best Places to Work
Job Details
We are looking for a highly motivated and talented mammalian expression specialist to join the ASF Protein Technologies group. This laboratory provides comprehensive molecular cloning, protein expression, purification and analytics support for the early stage pipeline of projects including both protein and small molecule therapeutics. The successful candidate will be a part of a team supporting lead identification of therapeutic proteins and protein reagent production for Amgen Research.
Responsibilities
- Work within a strong team of mammalian expression staff and interact with colleagues in protein engineering, molecular biology and protein biochemistry groups to deliver diverse protein reagents for research programs
- Hands-on transient and stable expression for a variety of protein classes; use analytical methods such as Vi-Cell, SDS-PAGE, Octet; must be an efficient multi-tasker with a highly proficient expression skillset and focus on detail
- Leverage knowledge in cell biology and state-of-art expression systems to enhance team's technical capabilities and drive development of processes which increase productivity and success with diverse protein classes
- Independently plan detailed procedures for projects including timelines and methods; analyzing and interpreting scientific data; providing regular updates about project results; and documenting experiments in lab notebooks and LIMS
- Collaborate with other Amgen Departments such as PKDM and Therapeutic Areas to advance therapeutic programs
Basic Qualifications
- Doctorate degree
OR - Master's degree and 4 years of scientific experience
OR - Bachelor's degree and 6 years of scientific experience
Preferred Qualifications
- Ph.D. degree with a focus on molecular biology or cell biology with strong protein expression component
- Ph.D. and postdoc from a leading institution or biotechnology company
- Biotech/pharma industry experience with emphasis on protein expression and production, especially with common mammalian transient and stable platforms as well as production in WAVE reactors or other disposable bioreactor technologies.
- Strong knowledge of cell biology, expression construct design, cell line engineering and expression strategies for broad classes of proteins including mAb, bispecific antibodies, immunogens, and membrane proteins.
- A track record of productivity, effective verbal and written communication and interpersonal skills, as well as the ability to work in a fast-paced team environment.
- Independent critical thinking and scientific achievement in research, exemplified by publications, conference presentations or generation of intellectual property.
Company
We are all different, yet we have this in common: our mission to serve patients. This sense of shared purpose is key to our becoming one of the world’s leading biotechnology companies. It guides us as we continue to launch new medicines and reach millions of patients worldwide.
We live the mission.
We win together.
We thrive on continual challenge.
Our team of 22,000+ scientists and professionals worldwide bring distinct perspectives and experiences to all we do. We leverage our global talent to achieve together—to research, manufacture and deliver ever-better products and greater depth to our mission.
At Amgen, there is a strong correlation between our high level of diversity and performance. Because addressing issues with a wider range of perspectives and approaches leads to more creative problem-solving. Together, we’re transforming the promise of science and biotechnology into therapies that have the power to restore health.
Connect with us to explore how you can Win, Live, and Thrive at Amgen.
- Website
- http://careers.amgen.com/
- Phone
- 805-447-1000
- Location
-
Corporate Headquarters
One Amgen Center Drive
Thousand Oaks
California
91320-1799
United States
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