Bristol-Myers Squibb Company

Research Scientist

Location
Redwood City, CA, United States
Posted
Jul 22, 2019
Ref
R1515765
Required Education
Bachelors Degree
Position Type
Full time
Summary

The Research Scientist will join the Integrated Oncology Discovery Research team at Bristol-Myers Squibb in Redwood City, CA and aide in the advancement of early stage therapeutic targets at the intersection of tumor genetics and tumor immunobiology. The qualified candidate is a highly motivated, interactive, and creative individual that possesses the ability to work across a highly matrixed environment to advance preclinical drug development programs from target identification/validation through IND enabling activities. The candidate will be expected to effectively collaborate with colleagues in the oncology, immunology, immuno-oncology, protein engineering/antibody development and medicinal chemistry groups. The successful candidate will demonstrate clear and professional verbal and written communication, capable of presenting scientific results to multidisciplinary teams and key stakeholders.

Position Requirements
  • A B.S. degree with a minimum of 8 years or a M.S. degree with a minimum of 6 years of industrial experience with strong scientific knowledge and research experience in cancer biology/cellular and molecular biology as well as experience in immune-oncology.
  • Demonstrated independence in experimental design, execution, data analysis and troubleshooting.
  • Knowledge of small molecule pre-clinical drugdevelopment including knowledge of designing assays and flowcharts to identify and optimize drug candidates.
  • Hands on experience with a wide range of in-vitro cellular and biochemical assays, including cell culture, western blotting, immunoprecipitation, ELISAs (MSD), reporter assays, siRNA/shRNA knockdown, CRISPR-mediated genome editing, qPCR, cloning, lentivirus generation and transduction
  • Experience with in vivo/ex vivo pharmacology, including working knowledge of in-vivo PK, PD and efficacy studies.
  • Experience in data mining through use of desktop tools/interfaces and public databases (e.g., UCSC genome Browser, CBIO, GTex, Oncoland etc).
  • Proficiency in utilizing software such as Graph Pad, Microsoft office etc. for data analysis and figure generation.
  • Ability to mentor more junior scientists and colleagues on best practices in the laboratory.
  • Attention to detail with excellent organizational and record keeping skills.
  • Excellent interpersonal skills with ability to interact effectively with people, internally and externally.
  • This position is located in Redwood City, CA. There will be less than 10% travel.