Sr Scientist, Yeast Library

Location
Seattle, WA
Posted
Jul 19, 2019
Ref
1696578789
Hotbed
BioForest
Required Education
Doctorate/PHD/MD
Position Type
Full time
Just is seeking a highly motivated and creative yeast display library expert that desires a significant opportunity to help invent the technologies required to improve worldwide access to biotherapeutics. This position will be part of a cross-discipline team developing antibody libraries for discovery, therapeutic optimization, and high throughput characterization. The successful candidate will be part of a cross-discipline team which will invent, design, and implement yeast display library methods to drive biotherapeutic development, with strong experience with library design and implementation methods, library screening methods such as FACS, and antibody yeast expression. This position will work closely with bioassay, bioanalytical, and process development colleagues in an integrated and collaborative environment

The successful candidate must also possess strong communication and collaboration skills, a desire to learn new scientific concepts and domains, and an ability to work directly with scientific staff across multiple disciplines.

Responsibilities:
• Work independently and in teams to develop, implement, and utilize antibody yeast libraries
• Design of expression vectors
• Perform high-throughput screening requiring some knowledge of laboratory robotics
• Collect, analyze, and act on NextGen Sequencing and FACS data
• Affinity characterize lead candidates
• Perform expressions and high throughput purifications of lead candidates
• Collaborate with scientific staff across multiple disciplines to accomplish goals

Qualifications and Education Requirements:
• Ph.D. or equivalent experience with strong experience in yeast display antibody library technologies
• Experience with affinity characterization
• Strong drive toward innovation
• Excellent verbal and written communication skills
• Strong focus on quality and attention to detail
• Possess effective task/time management organizational skills

Preferred qualifications:
• Experience in a biotherapeutic development environment
• Experience with high throughput bioassays
• Experience with epitope binning and mapping methods
• Experience in vector design and utilizing high-throughput, cost-effective DNA synthesis technologies
• Experience with other display technologies, protein secretion, cellular trafficking, and cell-surface capture and release methods
• Experience with genome integration, editing, and manipulation methods
• Ability to work in small groups as well as independently
• Ability to organize, analyze/interpret, and effectively communicate results

About Just

Just is an integrated design company focused on the technology of biotherapeutics from molecule through manufacturing plant. We believe that technological innovation will accelerate development and dramatically reduce the cost of these vital medicines. Just is developing a portfolio of molecules that best leverages our technological strengths. The Just mission: design and apply innovative technologies to dramatically expand global access to biotherapeutics. Come join our team of experts to help shape a better future.