Assistant Scientist or Scientist, Analytical R&D NBPI029

Location
San Diego, CA, United States
Posted
Jul 19, 2019
Ref
6bccc0f7
Hotbed
Biotech Beach
Required Education
Bachelors Degree
Position Type
Full time
Position: Assistant Scientist/Scientist, Analytical R&D

Reporting To: Associate Director, Analytical R&D

Core Competencies
  • Strong ability to apply scientific principles and critical thinking towards recognizing and solving pertinent problems is essential.
  • Effective communication skills (oral, written, presentation).
  • Able to plan and coordinate daily activities to align with department priorities/timelines and efficiently deliver on expectations.
  • Hands-on experience in analytical chromatography or oligonucleotide characterization.
  • Familiarity with cGMPs/GLPs and relevant regulations (ICH, FDA, EU) is a plus.
  • Strong preference is given to individuals experienced in routine cleaning, maintenance, and performance verification for HPLC systems and related hardware.
  • Must be proficient in basic software applications, including Microsoft Office.
  • Demonstrated experience with one or more scientific software applications is required.


Responsibilities
  • Performs routine analyses in support of chemistry, formulation, and biological research studies.
  • Provides testing support for method development and method validation.
  • Ensures data integrity; including proper documentation of experimental methods, results, and conclusions in laboratory notebooks.
  • Performs analytical data review for product stability and release.
  • Accurately follows SOPs related to safety, documentation, analytical methods, and corporate policies.
  • Maintains assigned laboratory equipment in a clean and safe manner, including routine operation and calibration.
  • Generates and/or reviews SOPs, certificates of analysis, analytical reports, and other documents.
  • Shows initiative in identifying technical or process improvement opportunities.
  • Follows safe laboratory practices according to corporate policies.
  • Other work as assigned based on the project and company needs.


Education and/or Experience:
  • Bachelor's or Master's Degree in Chemistry, Biochemistry, or related scientific discipline with 2+ years' experience in pharmaceutical industry with responsibilities in QC or analytical development.
  • Direct experience in at least one of the following:
    • Liquid chromatography (RP-HPLC, SEC, IEX) for purity/impurity analysis; mass spectrometry experience is a plus.
    • Bioanalytical method development, including analyte extractions from biological fluids.
    • Spectroscopic techniques (NMR, FTIR).
  • Experience working with nucleic acids, proteins, or nanoparticles is a plus.


Physical and Other Job Requirements:
  • Office/Lab environment. Lifting up to 50 pounds may be required. While performing the duties of this job, the employee is regularly required to use their hands and fingers to operate a computer keyboard, mouse, and telephone keypad or to write, as well as talk and hear. They are required to stand, walk or sit, reach with hands and arms, stoop, kneel, crouch or crawl. Specific vision abilities required by this job include close vision, distance vision, peripheral vision, depth perception and ability to focus.
  • This position splits its time between an office and laboratory environment. Lab work may include the use of centrifuges, microscopes, spectrometers and other laboratory tools. Will be required to wear personal protective equipment and comply with all safety regulations in the lab.


About Nitto BioPharma Inc.:

Description
Company Overview:
Nitto BioPharma, Inc., is a clinical stage biopharmaceutical company located in San Diego focused on the discovery and development of novel RNA-based therapeutics for intractable diseases. Clinical assets include a liver fibrosis program (BMS-986263/ND-L02-s0201), partnered with BMS and in Phase 2 in the US, an Idiopathic Pulmonary Fibrosis program (ND-L02-s0201) in Phase 2 in the US and Europe and Oncology program (NBF-006) in Phase 1 in the US . Nitto BioPharma is also advancing several programs for intractable diseases including Oncology and fibrosis.