Scientist I/II, Cellular & Molecular Biology - Investigative Toxicology & Pathology

Employer
AbbVie
Location
Lake County, IL, US
Posted
Jul 19, 2019
Ref
1903268
Required Education
Bachelors Degree
Position Type
Full time
The Investigative Toxicology and Pathology (ITP) Group in Preclinical Safety (PCS) is responsible for collaborating with Discovery to select new targets/lead molecules through use of in vitro and in vivo studies, as well as supporting toxicity-associated issue resolution for development programs. We have a challenging opportunity for a motivated and experienced Scientist in North Chicago, IL.

AbbVie is seeking a highly motivated, innovative, experienced, and collaborative scientist to perform immunohistochemistry (optimization and routine), in situ hybridization, image analysis, immunofluorescence/confocal microscopy, and laser capture microdissection for discovery and development project support.

Responsibilities:

  • Interface with ITP pathologists and toxicologists, as well as PCS Discovery and Development project team members to aid in the identification of new drug candidates and issue resolution
  • Collaborate with preclinical scientists to characterize target organ toxicity and morphologic endpoint quantification
  • Conceive and execute laboratory assays contributing to tissue localization of target and toxicity MOA determination in pre-clinical development
  • Level will be based on education & years of experience.


Qualifications (Required):
  • Bachelor's degree or equivalent education with typically 5 years experience, or Master's degree or equivalent education with typically 2 years experience.
  • Possesses thorough theoretical and practical understanding of immunohistochemistry, in situ hybridization, and image analysis.
  • Working knowledge of routine histotechnology


Qualifications (Preferred):

  • Strong experience in the use of commonly-used image analysis platforms (Genie, Halo, VisioPharm, etc.)
  • Pharmaceutical industry/biotechnology/toxicology experience
  • HT/HTL/QIHC (ASCP) certification
  • Working knowledge of immunofluorescence, confocal microscopy, and/or laser capture microdissection
  • Excellent oral and written communication skills.
  • Demonstrated ability to work collaboratively in cross-functional team setting