Research Associate (Discovery Biology)
- Employer
- Neurona Therapeutics
- Location
- South San Francisco, CA, United States
- Start date
- Jul 19, 2019
View more
- Discipline
- Science/R&D, Biology, Research
- Required Education
- Associate Degree
- Position Type
- Full time
- Hotbed
- Biotech Bay
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Research Associate (Discovery Biology)
Neurona Therapeutics is an early stage biotechnology company based in South San Francisco focused on the development of neuronal cell-based therapies for neurological disease. Our ideal candidate is a self-motivated individual who has a passion for scientific research. This is a fantastic opportunity to join a small team, work on transformative science, and take part in building an exciting, science-driven company.
Responsibilities include:
Required Qualifications:
Preferred Qualifications:
Neurona Therapeutics is an early stage biotechnology company based in South San Francisco focused on the development of neuronal cell-based therapies for neurological disease. Our ideal candidate is a self-motivated individual who has a passion for scientific research. This is a fantastic opportunity to join a small team, work on transformative science, and take part in building an exciting, science-driven company.
Responsibilities include:
- Maintain human pluripotent stem cells and differentiated cells.
- Perform stem cell differentiation into neuronal lineages using a large variety of formats, from 384 well plates to regular and large scale culture vessels.
- Develop screening cell based assays using automated liquid handler for stem cell differentiation optimization.
- Utilize High Content Screening (HCS) technology for high-throughput analysis of cell populations.
- Characterize differentiated cells using a panel molecular biology methods (immuno cyto-chemistry, Flow cytometry, RT-QPCR).
- Conduct fluorescence or magnetic -activated cell sorting experiments.
- Prepare tissue culture reagents (media, small molecules, cytokines); Tissue culture room upkeep and restocking.
- Maintain detailed records.
Required Qualifications:
- Bachelor's degree (+2 years of relevant experience) or Master degree in cell/molecular biology or related field.
- Clear knowledge of sterile tissue culture technique (at least two years experience).
- Familiar with pluripotent stem cell culture, in vitro directed differentiation paradigms and molecular/functional characterization of derived cell types.
- Experience with automated liquid handlers to perform medium / high throughput cell based screenings
- Willing to work a limited number of hours during weekends.
- Excellent writing, verbal communication, and interpersonal skills.
- Able to take initiative to improve work processes, develop innovative scientific methodologies and approaches to enhance research productivity.
Preferred Qualifications:
- At least one year of experience with human pluripotent (embryonic or induced) stem cell maintenance, differentiation, cell sorting and immuno cyto chemistry.
- One year of experience with lab automation for cell based screening assays using liquid handling automates (protocol creation, hands on automates)
- Experience with transcript- and protein-based gene expression analyses, high content screening.
- Knowledge of human developmental biology.
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