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Principal Scientist - Clinical Biomarkers Oncology

Employer
Amgen
Location
South San Francisco, CA, US
Start date
Jul 19, 2019

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Job Details

A biotechnology pioneer since 1980, Amgen was one of the first companies to realize the promise of this emerging science to bring safe, effective medicines from lab, to manufacturing plant, to patient. Amgen therapeutics have changed the practice of medicine, helping millions of people around the world in the fight against cancer, kidney disease, rheumatoid arthritis, and other serious illnesses. With a deep and broad pipeline of potential new medicines, Amgen remains committed to advancing science to dramatically improve people's lives.

The Clinical Biomarkers & Diagnostics department at Amgen is seeking a highly motivated Principal Scientist dedicated to clinical biomarker development in Oncology.

Integral to the ongoing success of Amgen's comprehensive biomarker programs, the clinical biomarkers team is responsible for developing and executing the biomarker strategy for each program by applying cutting edge, innovative technologies to advance science in support of Amgen's mission. The successful candidate is expected to work cross-functionally within Amgen and to interact closely with both the clinical development and discovery research groups. The position will focus on the development and execution of translational biomarker strategies to inform biochemical coverage, pharmacodynamics, mechanism of action, and patient stratification/selection in support of the progression of Amgen's pipeline candidates from late preclinical development through all stages of clinical development. The role is responsible for designing experiments, drafting and implementing protocols, executing studies, organizing data, drafting technical reports or tech transfer documents, and interpreting and communicating results to cross-functional teams.

Will interface with oncology research and is expected to work in a highly matrixed environment and drive scientific and technical innovation collaboratively with other members of the Clinical Biomarkers & Diagnostics function, as well as with the Amgen research community.

Amgen employees adhere to all corporate and local guidelines and regulations related to compliance and health and safety.

Basic Qualifications:

Doctorate degree and 3 years scientific experience

OR

Master's degree and 6 years of scientific experience

OR

Bachelor's degree and 8 years scientific experience

Preferred Qualifications:

PhD with 3+ years experience in implementing biomarker assays in a clinical trial setting and/or in preclinical biomarker discovery/validation

Knowledge and experience in oncology and/or immuno-oncology

Strong background in tumor biology and cancer genomics

Experience implementing a broad array of biomarker platforms and technologies to support a clinical program

Experience in assay development and qualification and analysis of clinical samples

Experience managing biomarker assay outsourcing processes with external vendors and CROs

Poise and professionalism with strong communication and influencing skills in a dynamic environment

Our culture is what makes Amgen a special place to work. We have a powerful shared purpose around our mission - to serve patients. We respect one another, recognize contributions, and have embedded collaboration, trust, empowerment and inclusion in all that we do.

Company

We are all different, yet we have this in common: our mission to serve patients. This sense of shared purpose is key to our becoming one of the world’s leading biotechnology companies. It guides us as we continue to launch new medicines and reach millions of patients worldwide.

We live the mission.

We win together.

We thrive on continual challenge.

Our team of 22,000+ scientists and professionals worldwide bring distinct perspectives and experiences to all we do. We leverage our global talent to achieve together—to research, manufacture and deliver ever-better products and greater depth to our mission.

At Amgen, there is a strong correlation between our high level of diversity and performance. Because addressing issues with a wider range of perspectives and approaches leads to more creative problem-solving. Together, we’re transforming the promise of science and biotechnology into therapies that have the power to restore health.

Connect with us to explore how you can Win, Live, and Thrive at Amgen.

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Company info
Website
Phone
805-447-1000
Location
Corporate Headquarters
One Amgen Center Drive
Thousand Oaks
California
91320-1799
United States

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