Process Development Associate Scientist

Thousand Oaks, CA, US
Jul 18, 2019
Required Education
Bachelors Degree
Position Type
Full time
Amgen is seeking a Process Development Associate Scientist to join the Pivotal Drug Substance Technologies organization in Thousand Oaks, CA. The pivotal DST organization is responsible for developing cell culture and purification manufacturing processes for Amgen's late stage pipeline.

Scope of work includes developing purification processes for recombinant proteins to maximize the recovery and purification yields, evaluating process robustness through process characterization, transferring processes to manufacturing, and conducting other relevant experiments such as for facility fit and raw material evaluation.

  • Design and execute purification experiments, mainly filtration and chromatography, at bench and pilot scale as needed
  • Document experimental data in lab notebooks
  • Analyze and interpret data with sound scientific understanding
  • Present data to the team and design follow-up experiments as needed
  • Author technical reports and regulatory filing documents
  • Transfer processes from process development to manufacturing and provide on-the-floor technical support and assist in trouble shooting as needed
  • Work with colleagues from the same function and cross functionally from analytical sciences, drug product, and manufacturing teams to meet deliverables for the project
  • Contribute to technology development projects to seek continuous improvement in reliability and efficiency

The Associate will have opportunities to cross train in cell culture development and become a well-rounded process development scientist with experience in upstream and downstream.

Basic Qualifications:

Master's degree and 2 years of scientific experience


Bachelor's degree and 4 years of scientific experience

Preferred Qualifications:
  • Degree in Chemical Engineering, Biochemistry, Biotechnology, Bioengineering, Biomedical engineering, or Bioprocessing discipline or relevant experience in the pharmaceutical or related industry preferred
  • 2+ years of biotech/pharma industry experience with emphasis on recombinant protein purification
  • Hands-on experience in chromatography (affinity, ion exchange, mixed mode, etc.) and filtration (depth filtration, tangential flow filtration), and good scientific understanding of these unit operations
  • Experience in Design of Experiments and statistical analysis
  • Strong oral and written communication skills
  • Self-motivated and strong organization skills
  • Strong interpersonal skills, and the ability to work in a dynamic and collaborative environment

Our culture is what makes Amgen a special place to work. We have a powerful shared purpose around our mission - to serve patients. We respect one another, recognize contributions, and have embedded collaboration, trust, empowerment and inclusion in all that we do.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.