Senior Research Associate, T Cell Engineering

We are seeking an experienced, creative and motivated Senior Research Associate to join our growing team in Emeryville. In this role, you will contribute to the company's efforts to develop next-generation cell therapies in solid tumor malignancies. Specifically, you will be part of a cell biology research team focused on engineering approaches to enhance CAR T anti-tumor activity.

The successful candidate will have a strong immunology background and will be expected to work in a collaborative cross-functional team environment, perform experiments, organize and analyze results, communicate effectively and present findings in team meetings.

Responsibilities include, but are not limited to:

• Employ viral based strategies for the genetic modification of T cells with chimeric antigen receptors (CARs).
• Culture and characterize CAR T cells
• Plan and execute in vitro functional assays with human T cells according to project timelines and goals
• Assist in the design of new next-generation CAR T receptors
• Assist in the design of murine models/experiments to evaluate CAR T cell function in vivo
• Maintain up-to-date knowledge of immunotherapy field
• Coordinate tasks across projects, demonstrating prioritization and planning
• Effectively communicate plans and results in both oral and written form
• Other duties as assigned

Qualifications and Experience

• BS or MS degree in Immunology/Cell Biology
• 5+ years Industry/academic experience in the Immunology/immunotherapy field (Immunotherapy background strongly preferred)

• Excellent mammalian cell/tissue culture and sterile technique required
• Experience with multi-color flow cytometry and data analysis (FACSDiva, FlowJo) required
• Experience with primary T cell-based assays (cytotoxicity assays, cell proliferation assays, cytokine secretion etc.) required
• Experience in viral gene delivery required
• Experience with automated liquid handling equipment and procedures desired
• Prior experience with small molecules desired
• Strong organizational skills and record keeping
• Self-motivated and willing to accept temporary responsibilities outside of initial job description
• Comfortable in a fast-paced company and able to adjust workload based upon changing priorities
• Excellent interpersonal, verbal and written communication skills are essential in this collaborative work environment

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Kite is a biopharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid, long-term durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered cell therapies designed to empower the immune system's ability to recognize and kill tumors. Kite is based in Santa Monica, CA. For more information on Kite, please visit www.kitepharma.com. Sign up to follow @KitePharma on Twitter at www.twitter.com/kitepharma.

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